Chromosomal Instability in Cancer Cells

Language: English

Published by Springer International Publishing Sep 2015, 2015

3319202901 / 9783319202907

Series: Book 141 of 157 - Recent Results in Cancer Research

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Seller: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, GermanyBuchWeltWeit Ludwig Meier e.K.

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This item is printed on demand - it takes 3-4 days longer - Neuware -This issue of Recent Results in Cancer Research presents a comprehensive review of current understanding of chromosomal instability in cancer and of strategies to use this information for better treatment of patients with cancer. Cancer is a disease of the chromosomes, and chromosomal instability in cancer disrupts gene function by either inactivating tumor suppressor genes or activating growth-promoting oncogenes. The chromosomal basis for these aberrations is either translocations, which change the integrity of genes, or abnormal numbers of chromosomes, a condition referred to as aneuploidy, which results in abnormal gene expression levels. Such structural or numerical chromosomal aberrations are specific for distinct tumor entities. The degree of chromosomal instability and the degree of intratumor heterogeneity have profound consequences for disease outcome and for therapeutic stratification. 232 pp. Englisch.

Seller Inventory # 9783319202907

Title
Chromosomal Instability in Cancer Cells
Author
Thomas Ried
Publisher
Springer International Publishing Sep 2015
Publication year
2015
Condition
Neu
Binding
Buch
Language
English
ISBN 10
3319202901
ISBN 13
9783319202907
Item weight
518 grams
Dimensions
241x160x19 mm
Series
Book 141 of 157: Recent Results in Cancer Research

BuchWeltWeit Ludwig Meier e.K.

Bergisch Gladbach, Germany

5-star seller

AbeBooks seller since January 11, 2012

Shipping rates from Germany to U.S.A.

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First itemUS$ 25.79US$ 25.79
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BuchWeltWeit Ludwig Meier e.K.

Germany