Although acute inflammation is a healthy physiological response indicative of wound healing, chronic inflammation has been directly implicated in a wide range of degenerative human health disorders encompassing almost all present day non-communicable diseases including autoimmune diseases, obesity, diabetes and atherosclerosis. Chronic Inflammation: Molecular Pathophysiology, Nutritional and Therapeutic Interventions provides an exposition of the process of chronic inflammation in three parts:
- Systems Biology of Inflammation and Regulatory Mechanisms describes the process of chronic inflammation including initiation, progression, and resolution.
- Pathologies Associated with Inflammation gives a rigorous and critical treatment of specific human health disorders where chronic inflammation plays a major role.
- Nutrition & Therapeutics for Inflammatory Diseases details the protective abilities of structurally diverse antioxidants, phytochemicals, anti-inflammatory diets, omega-3 fatty acids, NSAIDs, disease modifying anti-rheumatic drugs, and novel regimens.
Designed for scientists as well as clinicians, Chronic Inflammation provides critical understanding of the key checkpoints that regulate chronic inflammation. Going beyond the epidemiology of chronic inflammation, the text covers regulatory mechanisms controlling inflammation initiation, progression, and resolution. The authors address pathologies associated with inflammation and provide various nutritional and therapeutic interventions for inflammatory diseases.
Sashwati Roy, PhD, is an Associate Professor in the Department of Surgery and Director, Laser Capture Molecular Core in the College of Medicine, Ohio State University, Columbus.
Debasis Bagchi, PhD, is a Professor in the Department of Pharmacological and Pharmaceutical Sciences at University of Houston, Texas. His research interests include free radicals, human diseases, carcinogenesis, pathophysiology, mechanistic aspects of cytoprotection by antioxidants, regulatory pathways in obesity, and gene expression.
Siba P. Raychaudhuri, MD, is the Chief of the Rheumatology Division at the VA Medical Center in Sacramento, California, and a Clinical Assistant Professor in the Division of Rheumatology, Allergy and Clinical Immunology at the University of California, Davis. Dr. Raychaudhuri’s major research focus is to understand the molecular mechanisms of immune-mediated inflammatory diseases.
