Clinical Guidelines for sperm DNA Fragmentation of Male Infertility

Language: English

Published by LAP LAMBERT Academic Publishing Jun 2021, 2021

6203870544 / 9786203870541

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This item is printed on demand - Print on Demand Titel. Neuware -Description:Sperm DNA integrity is crucial for fertilization and development of healthy offspring. The spermatozoon undergoes extensive molecular remodeling of its nucleus during later phases of spermatogenesis, which imparts compaction and protects the genetic content. Testicular (defective maturation and abortive apoptosis) and post-testicular (oxidative stress) mechanisms are implicated in the etiology of sperm DNA fragmentation (SDF), which affects both natural and assisted reproduction. Several clinical and environmental factors are known to negatively impact sperm DNA integrity. An increasing number of reports emphasizes the direct relationship between sperm DNA damage and male infertility. Currently, several assays are available to assess sperm DNA damage, however, routine assessment of SDF in clinical practice is not recommended by professional organizations. This article provides an overview of SDF types, origin and comparative analysis of various SDF assays while primarily focusing on the clinical indications of SDF testing. Importantly, we report four clinical cases where SDF testing had played a significant role in improving fertility outcome.VDM Verlag, Dudweiler Landstraße 99, 66123 Saarbrücken 224 pp. Englisch.…

Seller Inventory # 9786203870541

Title
Clinical Guidelines for sperm DNA Fragmentation of Male Infertility
Author
Marcuse F. Steven
Publisher
LAP LAMBERT Academic Publishing Jun 2021
Publication year
2021
Condition
Neu
Binding
Taschenbuch
Language
English
ISBN 10
6203870544
ISBN 13
9786203870541
Item weight
352 grams
Dimensions
220x150x15 mm

buchversandmimpf2000

Emtmannsberg, BAYE, Germany

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