Clustering, Cluster Inference and Applications in Clustering: Applications to the Analysis of Gene Expression Data

Ray, Surajit

ISBN 10: 3845423625 / ISBN 13: 9783845423623

Published by LAP LAMBERT Academic Publishing, 2011

About this Item

LIKE NEW. SHIPS FROM MULTIPLE LOCATIONS.

Seller Inventory # ERICA79638454236256

Bibliographic Details

• Title: Clustering, Cluster Inference and Applications in Clustering: Applications to the Analysis of Gene Expression Data
• Publisher: LAP LAMBERT Academic Publishing
• Publication Date: 2011
• Language: English
• ISBN 10: 3845423625
• ISBN 13: 9783845423623
• Binding: Paperback
• Condition: Like New
• Book Type: book

About this title

Synopsis

Multivariate mixture models provide a convenient method of density estimation and model based clustering as well as providing possible explanations for the actual data generation process. But the problem of choosing the number of components in a statistically meaningful way is still a subject of considerable research. Available methods for estimation include, optimizing AIC and BIC, estimating the number through nonparametric maximum likelihood, hypothesis testing and Bayesian approaches with entropy distances. In our book we present several rules for selecting a finite mixture model, based on estimation and inference using a quadratic distance measure. In this book we also develop tools for determining the number of modes in a mixture of multivariate normal densities. We use these criterion to select clusters which display distinct modes. Finally we fine tune our methods to analyze gene-expression data from micro-arrays, and compare them with other competitive methods.

About the Author

Surajit Ray is an assistant professor of Statistics in the Department of Mathematics and Statistics at Boston University. His research interests are in the area of statistical model selection, the theory and geometry of mixture models and functional data analysis. He is especially interested in challenges presented by "large magnitude".