Complement in Health and Disease

Language: English

Published by Springer, Springer Okt 2012, 2012

9401049815 / 9789401049818

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This item is printed on demand - Print on Demand Titel. Neuware -Since the first edition of Complement in Health and Disease was published in 1986, significant advances have been made. The cDNAs for all of the components and some of the receptors have been cloned and sequenced. The chromosomal localization and the structural organization of a number of these genes have now been determined. These advances are now facilitating research into the structure of the complement proteins, the nature of the complement deficiency syndromes, the regulation of complement gene expression and the role of complement in different diseases. This edition contains contributions from both basic and clinical scientists in a format which we hope will appeal to both immunologists and physicians who wish to know more about this fascinating and important host defence system. The introductory chapter by John Weiler presents a historical background to research on the complement system and describes the biochemical events occurring during activation of the system. In Chapter 2 Alastair Dodds and Tony Day discuss the phylogeny and evolution of the complement system. The techniques of protein chemistry and molecular biology have provided powerful insights into the modular structure of complement proteins and the evolution of the complement system. The structure and organisation of the complement genes is described in Chapter 3 by Ken Reid and Duncan Campbell. This chapter describes the modular structure of the complement proteins and some of the mutations which are responsible for deficiencies of individual components.Springer-Verlag KG, Sachsenplatz 4-6, 1201 Wien 396 pp. Englisch.…

Seller Inventory # 9789401049818

Title
Complement in Health and Disease
Author
K. Whaley
Publisher
Springer, Springer Okt 2012
Publication year
2012
Condition
Neu
Binding
Taschenbuch
Language
English
ISBN 10
9401049815
ISBN 13
9789401049818
Edition
2nd Edition
Item weight
598 grams
Dimensions
235x155x22 mm

buchversandmimpf2000

Emtmannsberg, BAYE, Germany

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