Comprehensive Chirality

Comprehensive Chirality, Second Edition is the definitive ten-volume reference, offering a thorough exploration of chiral research and application. This extensively updated edition features 121 new chapters and 70 revised ones, focusing on the latest advancements in chiral research across synthesis, catalysis, analytical chemistry, and bioactive compound synthesis. Edited by a world-class editorial board, with contributions from leading experts, Comprehensive Chirality, Second Edition bridges theoretical principles with practical applications, making it an invaluable resource for advanced students, researchers, and professionals.

Key highlights include:
- Innovative Reactions and Methods: advanced diastereo- and enantioselective techniques for controlling stereogenic centers in complex natural products and pharmaceuticals.
- Chiral Auxiliaries and Modern Reagents: transformative uses of chiral auxiliaries and cutting-edge reagents such as hypervalent iodide.
- Catalytic Methodologies: comprehensive coverage of C-C bond formation, emphasizing transition metals, biocatalysis, and multicatalysis.
- Asymmetric Photochemistry: light-induced asymmetric transformations.
- Olefin Functionalization and Cycloaddition: asymmetric oxidation and reduction methods.
- Biocatalysis and Enzyme Engineering: in-depth analysis of enzyme design and engineering as powerful synthesis catalysts.
- Industrial Applications: practical insights into asymmetric synthesis for industrial applications, illustrated through recent case studies.
- Spectroscopic Techniques: updated spectroscopic methods for separating and analyzing enantiomers.

• Unites different areas of research and allows anyone working or researching in chiral chemistry to navigate through the most essential concepts
• Includes different areas of research and deep foundational reviews
• Helps users apply context to diverse journal literature, aiding them in identifying areas for further research and/or for solving problems
• Serves as a valuable, critical tool for instructors, practicing experimentalists, and students of the field, as well as those curious to gain appreciation of the chirality landscape and its vast expanse

Janine Cossy

Molecular, Macromolecular Chemistry and Materials (C3M)

ESPCI Paris, PSL University, CNRS, 75005 Paris, France

Professor Janine Cossy graduated from the University of Reims (France) working under the supervision of Prof. Jean-Pierre Pète. After a postdoctoral stay with Prof. Barry Trost (1980-1982) at the University of Wisconsin (USA), she returned to Reims where she became Director of Research CNRS in 1990. The same year, she moved to Paris to become Professor of Organic Chemistry at the Ecole Supérieure de Physique et de Chimie Industrielles de la Ville de Paris (ESPCI Paris). She has published more than 560 articles and filed 18 patents in the field of synthetic organic chemistry and natural product synthesis. She was Associate Editor at Organic Letters from 2005 to 2018 and since October 2023, she is Tetrahedron Associate Editor. Her research efforts have resulted in more than 560 publications and 18 patents. Among the awards, she received: the CNRS Silver Medal (France, 1996); the UK Royal Society Rosalyn Franklin International Lecturership awarded to internationally recognized women scientists (UK, 2005); the E. C. Taylor Senior Award (2015); the IUPAC 2019 Distinguished Women in Chemistry or Chemical Engineering (2019). She was elected at the French Academy of sciences in 2017 and in 2022, she has been elected at the national Academy of Pharmacy. In addition, she was nominated Chevalier de l’Ordre National du Mérite and promoted to Officier in 2018. In 2013, she was nominated Chevalier de la Légion d’Honneur and was promoted to Officier in 2023. She is the co-funder of two companies: CDP-Innovation and Acanthe Biotech.

Affiliations

Molecular, Macromolecular Chemistry and Materials (C3M)

ESPCI Paris, PSL University, CNRS, 75005 Paris, France

Expertise

Development of synthetic methods: Enantioselective reactions, rearrangements, radicals, photochemistry, organometallic reactions, biocatalysis, plasma reactions. Synthesis of natural products and/or bioactive compounds.