Comprehensive Management of Arteriovenous Malformations of the Brain and Spine

Vascular malformations of the brain and spine pose many management challenges. This text provides a comprehensive, state-of-the-art review of the natural history, treatment options, and outcomes of patients with these conditions. Despite their relative rarity, these lesions are responsible for devastating injury to individuals and can cause an enduring physical, psychological, and economic burden on patients and families. Many new therapeutic options are now available with the advent of novel surgical, endovascular, and radiosurgical techniques. The basic sciences have fuelled development of small molecule and biologic therapies targeting the molecular basis of disease. Authored by international experts in the fields of neurosurgery, neurology, radiology, and radiation oncology, this book provides state-of-the-art treatment plans and discussions of ideal therapy. This text is aimed at practitioners in the fields of neurology, neurosurgery, neuroradiology, radiation oncology, rehabilitation medicine and allied fields who care for patients with brain and spinal vascular malformations.

Robert F. Spetzler, MD is the J. N. Harber Chairman of Neurological Surgery and Director of the Barrow Neurological Institute, Phoenix, AZ, USA.

Douglas S. Kondziolka, MD, MSc, FRCSC, FACS is Professor of Neurosurgery; Vice-Chair, Clinical Research (Neurosurgery); Professor of Radiation Oncology; and Director, Center for Advanced Radiosurgery, NYU Langone Medical Center, New York, NY, USA.

Randall T. Higashida, MD is Clinical Professor of Radiology, Neurological Surgery, Neurology, and Anesthesiology, and Chief of the Division of Interventional Neurovascular Radiology at the University of California San Francisco Medical Center, San Francisco, CA, USA.

M. Yashar S. Kalani, MD, PhD is Assistant Professor of Neurological Surgery at the Barrow Neurological Institute, Phoenix, AZ, USA.