Computation of Biomolecular Structures

Language: English

Published by Springer, Springer Vieweg Dez 2011, 2011

3642778003 / 9783642778001

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This item is printed on demand - Print on Demand Titel. Neuware -Computational techniques have become an indispensable part of Molecular Biology, Biochemistry, and Molecular Design. In conjunction with refined experimental methods and powerful hardware, they enable us to analyze and visualize biomolecular structures, simulate their motions and to a variable degree understand their physicochemical properties and function. In addition, they provide essentially the only way to analyze and correlate the astronomical amounts of experimental sequence and structural data accumulating in international databases. We have good reasons to believe that further advances in this area will eventually enable us to predict with sufficient accuracy many structural and functional properties of fairly large biomolecules, given their sequence and specified environmental conditions. However, it is also important to realize that in achieving this goal, we encounter several serious problems of conceptual and methodological nature, the solution of which requires new approaches and algorithms. For example, we need better force fields, more efficient optimization routines, an adequate description of electrostatics and hydration, reliable methods to compute free energies, and ways to extent the length of molecular dynamics simulations by several orders of magnitude.Springer-Verlag KG, Sachsenplatz 4-6, 1201 Wien 264 pp. Englisch.…

Seller Inventory # 9783642778001

Title
Computation of Biomolecular Structures
Author
Dikeos M. Soumpasis
Publisher
Springer, Springer Vieweg Dez 2011
Publication year
2011
Condition
Neu
Binding
Taschenbuch
Language
English
ISBN 10
3642778003
ISBN 13
9783642778001
Item weight
406 grams
Dimensions
235x155x15 mm

buchversandmimpf2000

Emtmannsberg, BAYE, Germany

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