Title: Computational Approaches In Molecular Interaction Analysis: Predicting Protein Complexes, Host-pathogen Interactions, And Protein Function From Interactome Data
Publisher: WSPC
Publication Date: 2025
Language: English
ISBN 10: 9819807174
ISBN 13: 9789819807178
Binding: Hardcover
Condition: New

About this title

Synopsis

This book presents a curated collection of research articles from the Journal of Bioinformatics and Computational Biology, highlighting advances in protein-protein interaction-based computational methods for predicting protein complexes, host-pathogen interactions (HPIs), and protein functions. In Part I, it addresses the dynamic challenges of protein complex prediction using innovative techniques like GECA and IPC-RPIN, which integrate network topology, gene expression, and GO annotations to improve accuracy, especially for small complexes. Part II focuses on HPIs, reviewing computational approaches, predictive models, and tools that enhance understanding of infectious diseases, with a particular emphasis on machine learning applications. Part III delves into protein function prediction, employing PPI networks, multi-label methods, and iterative models that account for dynamic interactions. Collectively, these studies provide a comprehensive resource for advancing computational biology and understanding cellular and disease mechanisms.

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