Computational Methods for Estimating the Kinetic Parameters of Biological Systems

Language: English

Published by Springer Dez 2021, 2021

1071617664 / 9781071617663

Series: Book 102 of 382 - Methods in Molecular Biology

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This item is printed on demand - Print on Demand Titel. Neuware -Current Approaches of Building Mechanistic Pharmacodynamic Drug-Target Binding Models.- An Extended Model Including Target Turnover, Ligand-Target Complex Kinetics, and Binding Properties to Describe Drug-Receptor Interactions.- Beyond the Michaelis-Menten: Bayesian Inference for Enzyme Kinetic Analysis.- Multi-Objective Optimization Tuning Framework for Kinetic Parameter Selection and Estimation.- Relationship between Dimensionality and Convergence of Optimization Algorithms: A Comparison between Data-Driven Normalization and Scaling Factor-Based Methods Using PEPSSBI.- Dynamic Optimization Approach to Estimate Kinetic Parameters of Monod-Based Microalgae Growth Models.- Automatic Assembly and Calibration of Models of Enzymatic Reactions Based on Ordinary Differential Equations.- Data Processing to Probe the Cellular Hydrogen Peroxide Landscape.- Computational Methods for Structure-Based Drug Design through Systems Biology.- Model Setup and Procedures for Prediction of Enzyme Reaction Kinetics with QM-Only and QM:MM Approaches.- The Role of Ligand Rebinding and Facilitated Dissociation on the Characterization of Dissociation Rates by Surface Plasmon Resonance (SPR) and Benchmarking Performance Metrics.- Computational Tools for Accurate Binding Free Energy Prediction.- Computational Alanine Scanning Reveals Common Features of TCR/pMHC Recognition in HLA-DQ8-Associated Celiac Disease.- Umbrella Sampling-Based Method to Compute Ligand-Binding Affinity.- Creating Maps of the Ligand Binding Landscape for Kinetics-Based Drug Discovery.- Prediction of Protein-Protein Binding Affinities from Unbound Protein Structures.- Parameter Optimization for Ion Channel Models: Integrating New Data with Known Channel Properties.Libri GmbH, Europaallee 1, 36244 Bad Hersfeld 392 pp. Englisch.…

Seller Inventory # 9781071617663

Title
Computational Methods for Estimating the Kinetic Parameters of Biological Systems
Author
Quentin Vanhaelen
Publisher
Springer Dez 2021
Publication year
2021
Condition
Neu
Binding
Buch
Language
English
ISBN 10
1071617664
ISBN 13
9781071617663
Item weight
932 grams
Dimensions
260x183x27 mm
Series
Book 102 of 382: Methods in Molecular Biology

buchversandmimpf2000

Emtmannsberg, BAYE, Germany

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AbeBooks seller since January 23, 2017

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