Computer-Aided Drug Design: Development of New Heterocyclic Molecules

Language: English

Published by LAP LAMBERT Academic Publishing Jun 2022, 2022

6204980866 / 9786204980867

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This item is printed on demand - Print on Demand Titel. Neuware -The application of computer-assisted drug design methods to the identification of new inhibitors targeting the responsible receptors of the studied diseases is described in this book. After synthesizing a range of analogs, a structure-activity relationship (SAR) may be established, and the SAR could then be utilized as a guideline for future synthesis and optimization. Computer simulations of ligand-receptor complexes provide also structural insights into the interactions, allowing the hit-to-lead optimization process to be rationally driven. Further, Lipinski's rule of five and ADMET prediction were performed to identify new inhibitors for the above targets. The designed lead compounds pave the way for the development of safe and effective clinical candidates that might one day be used to treat the above-mentioned diseases. We will focus our discussion in this book on the several intriguing scientific papers published by our research group in a variety of international journals.VDM Verlag, Dudweiler Landstraße 99, 66123 Saarbrücken 160 pp. Englisch.…

Seller Inventory # 9786204980867

Title
Computer-Aided Drug Design: Development of New Heterocyclic Molecules
Author
Khalil El Khatabi
Publisher
LAP LAMBERT Academic Publishing Jun 2022
Publication year
2022
Condition
Neu
Binding
Taschenbuch
Language
English
ISBN 10
6204980866
ISBN 13
9786204980867
Item weight
256 grams
Dimensions
220x150x10 mm

buchversandmimpf2000

Emtmannsberg, BAYE, Germany

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AbeBooks seller since January 23, 2017

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