Computer-Aided Drug Discovery

Wei Zhang

ISBN 10: 1493935194 / ISBN 13: 9781493935192

Published by Springer New York, Springer US, 2016

About this Item

Druck auf Anfrage Neuware - Printed after ordering - This detailed volume examines computer-aided drug discovery (CADD), a crucial component of modern drug discovery programs that is widely utilized to identity and optimize bioactive compounds for the development of new drugs. With a focus on the methods that are commonly used in the early stage of drug discovery, chapters explore computer simulation, structure prediction, conformational sampling, binding site mapping, docking and scoring, in silico screening, and fragment-based drug design. In addition to the state-of-the-art theoretical concept, this book also includes step-by-step, readily reproducible computational protocols as well as examples of various CADD strategies. The limitations and potential pitfalls of different computational methods are discussed by experts, and tips and advice for their applications are suggested.Practical and thorough, Computer-Aided Drug Discovery serves as an ideal addition to theMethods in Pharmacology and Toxicology series, guiding researchers toward their lab's goals with this exciting and versatile technology.

Seller Inventory # 9781493935192

Bibliographic Details

• Title: Computer-Aided Drug Discovery
• Publisher: Springer New York, Springer US
• Publication Date: 2016
• Language: English
• ISBN 10: 1493935194
• ISBN 13: 9781493935192
• Binding: Buch
• Condition: Neu
• Dimensions: 260W x 183H x 23D millimeters 260 millimeters width by 183 millimeters height by 23 millimeters depth
• Weight: 801 grams

About this title

Synopsis

This detailed volume examines computer-aided drug discovery (CADD), a crucial component of modern drug discovery programs that is widely utilized to identity and optimize bioactive compounds for the development of new drugs. With a focus on the methods that are commonly used in the early stage of drug discovery, chapters explore computer simulation, structure prediction, conformational sampling, binding site mapping, docking and scoring, in silico screening, and fragment-based drug design.  In addition to the state-of-the-art theoretical concept, this book also includes step-by-step, readily reproducible computational protocols as well as examples of various CADD strategies.  The limitations and potential pitfalls of different computational methods are discussed by experts, and tips and advice for their applications are suggested.

Practical and thorough, Computer-Aided Drug Discovery serves as an ideal addition to the Methods in Pharmacology and Toxicology series, guiding researchers toward their lab’s goals with this exciting and versatile technology.