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Bibliographic Details

Title: Computer Techniques in Preclinical and Clinical Drug Development
Publisher: CRC Press -
Publication Date: 1996
Language: English
ISBN 10: 0849376823
ISBN 13: 9780849376825
Binding: hardcover
Condition: Very Good

About this title

Synopsis

It is estimated that 80 to 90% of drugs under development never make it to the marketplace due to insufficient clinical activity, unacceptable toxicity, rapid appearance of drug resistance, or other factors that should be, at least partially, predictable from preclinical testing. This new text asks the question, "How can we use computational methods to improve the success rate in drug development?" Computer Techniques in Preclinical and Clinical Drug Development shows how modeling makes it possible to extract the maximum amount of information and predictive value from preclinical data. Computer modeling methods from the areas of pharmacokinetics, pharmacodynamics, cytokinetics, and inhibition kinetics of multi-enzyme pathways are all discussed in this unique reference source.

About the Author

Jackson, Robert C.

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