Druck auf Anfrage Neuware - Printed after ordering - Leading experts provide timely and comprehensive information on methods for conditional mutagenesis in the mouse (part 1) and their application to model human physiology and pathophysiology (part 2). It illustrates how sophisticated genetic manipulations of the mouse genome are employed to model human diseases and to identify underlying molecular mechanisms. Finally the book considers the development of new drugs to treat them.

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Bibliographic Details

Title: Conditional Mutagenesis: An Approach to Disease Models
Publisher: Springer, Springer Vieweg
Publication Date: 2006
Language: English
ISBN 10: 3540351086
ISBN 13: 9783540351085
Binding: Buch
Condition: Neu
Dimensions: 241 millimeters width by 160 millimeters height by 35 millimeters depth
Weight: 975 grams

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Synopsis

Leading experts provide timely and comprehensive information on methods for conditional mutagenesis in the mouse (part 1) and their application to model human physiology and pathophysiology (part 2). It illustrates how sophisticated genetic manipulations of the mouse genome are employed to model human diseases and to identify underlying molecular mechanisms. Finally the book considers the development of new drugs to treat them.

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"This is a comprehensive overview of generating mouse models with conditional modification of genes to study the effects of gene dysfunction in the development of human diseases. ... The authors target general scientific researchers ... . This book will be very informative for any scientists and students interested in using or generating genetically modified mouse models in biomedical research. ... an excellent reference on the most recent progress in generating conditional knockout mice." (Grace L Guo, Doody’s Review Service, July, 2008)

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