Conditional Mutagenesis: An Approach to Disease Models

Robert Feil

ISBN 10: 3540351086 / ISBN 13: 9783540351085

Published by Springer, Springer Vieweg Nov 2006, 2006

About this Item

This item is printed on demand - Print on Demand Titel. Neuware -Leading experts provide timely and comprehensive information on methods for conditional mutagenesis in the mouse (part 1) and their application to model human physiology and pathophysiology (part 2). It illustrates how sophisticated genetic manipulations of the mouse genome are employed to model human diseases and to identify underlying molecular mechanisms. Finally the book considers the development of new drugs to treat them.Springer-Verlag KG, Sachsenplatz 4-6, 1201 Wien 544 pp. Englisch.

Seller Inventory # 9783540351085

Bibliographic Details

• Title: Conditional Mutagenesis: An Approach to Disease Models
• Publisher: Springer, Springer Vieweg Nov 2006
• Publication Date: 2006
• Language: English
• ISBN 10: 3540351086
• ISBN 13: 9783540351085
• Binding: Buch
• Condition: Neu
• Dimensions: 241W x 160H x 35D millimeters 241 millimeters width by 160 millimeters height by 35 millimeters depth
• Weight: 975 grams

About this title

Synopsis

Leading experts provide timely and comprehensive information on methods for conditional mutagenesis in the mouse (part 1) and their application to model human physiology and pathophysiology (part 2). It illustrates how sophisticated genetic manipulations of the mouse genome are employed to model human diseases and to identify underlying molecular mechanisms. Finally the book considers the development of new drugs to treat them.

Review

From the reviews:

"This is a comprehensive overview of generating mouse models with conditional modification of genes to study the effects of gene dysfunction in the development of human diseases. ... The authors target general scientific researchers ... . This book will be very informative for any scientists and students interested in using or generating genetically modified mouse models in biomedical research. ... an excellent reference on the most recent progress in generating conditional knockout mice." (Grace L Guo, Doody’s Review Service, July, 2008)