The Consequences of Chromosome Imbalance : Principles, Mechanisms, and Models

Language: English

Published by Cambridge University Press, 2007

052103809X / 9780521038096

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Seller: AHA-BUCH GmbH, Einbeck, GermanyAHA-BUCH GmbH

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Druck auf Anfrage Neuware - Printed after ordering - This book considers in detail the mechanisms of a major human problem. Chromosome imbalance affects all stages of life in ways ranging from spontaneous abortion and retardation to behavioural problems and malignancy. Charles J. Epstein concerns himself with how and why a particular chromosome imbalance produces a specific phenotype. His fundamental goal is to connect chromosome aberrations with functional abnormalities in terms of gene expression, developmental and cell biology, and metabolism. Through his examination of this relationship, we learn more about normal development and function. The book begins with an exploration of several human autosomal aneuploid phenotypes, with particular emphasis on the relationship between genotype and phenotype. In the next part, broad theoretical considerations of the mechanisms which generate these phenotypes are examined with reference to studies on man and other organisms such as bacteria and mice. Experimental approaches to study the effects of aneuploidy are presented next with special attention paid to the development of model systems for studying human aneuploidy.…

Seller Inventory # 9780521038096

Title
The Consequences of Chromosome Imbalance : Principles, Mechanisms, and Models
Author
Charles J. Epstein
Publisher
Cambridge University Press
Publication year
2007
Condition
Neu
Binding
Taschenbuch
Language
English
ISBN 10
052103809X
ISBN 13
9780521038096
Item weight
769 grams
Dimensions
234x156x27 mm

AHA-BUCH GmbH

Einbeck, Germany

5-star seller

AbeBooks seller since August 14, 2006

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