Current Aspects of Radiopharmaceutical Chemistry

ISBN 10: 3038971626 / ISBN 13: 9783038971627

Published by Mdpi AG, 2018

About this Item

Print on Demand pp. 216.

Seller Inventory # 380626299

Bibliographic Details

• Title: Current Aspects of Radiopharmaceutical Chemistry
• Publisher: Mdpi AG
• Publication Date: 2018
• Language: English
• ISBN 10: 3038971626
• ISBN 13: 9783038971627
• Binding: Soft cover
• Condition: New

About this title

Synopsis

Positron emission tomography (PET) and single-photon emission computed tomography (SPECT) are in vivo molecular imaging techniques which are widely used in nuclear medicine for the diagnosis and treatment follow-up of many major diseases. They use biomolecules as probes, which are labeled with radionuclides of short half-lives, synthesized prior to the imaging studies. These probes are called radiopharmaceuticals. Their design and development require a rather interdisciplinary process involving many different disciplines of natural and health sciences. In addition to their diagnostic and therapeutic purposes in the field of nuclear medicine, radiopharmaceuticals provide powerful tools for in vivo pharmacology during the process of pre-clinical drug development to identify new drug targets, investigate the pathophysiology of diseases, discover potential drug candidates, and evaluate the pharmacokinetics and pharmacodynamics of drugs in vivo. Furthermore, they allow molecular imaging studies in various small-animal models of disease, including genetically engineered animals. The current collection of articles provides unique examples covering all major aspects in the field.