DEVELOPMENT AND VALIDATION OF HPLC METHOD OF ROSUVASTATIN SODIUM | Analytical method of Rosuvastatin Sodium

Prabhakar Verma

ISBN 10: 6206146502 / ISBN 13: 9786206146506

Published by LAP LAMBERT Academic Publishing, 2023

About this Item

DEVELOPMENT AND VALIDATION OF HPLC METHOD OF ROSUVASTATIN SODIUM | Analytical method of Rosuvastatin Sodium | Prabhakar Verma | Taschenbuch | Englisch | 2023 | LAP LAMBERT Academic Publishing | EAN 9786206146506 | Verantwortliche Person für die EU: preigu GmbH & Co. KG, Lengericher Landstr. 19, 49078 Osnabrück, mail[at]preigu[dot]de | Anbieter: preigu.

Seller Inventory # 126788880

Bibliographic Details

• Title: DEVELOPMENT AND VALIDATION OF HPLC METHOD OF ROSUVASTATIN SODIUM | Analytical method of Rosuvastatin Sodium
• Publisher: LAP LAMBERT Academic Publishing
• Publication Date: 2023
• Language: English
• ISBN 10: 6206146502
• ISBN 13: 9786206146506
• Binding: Taschenbuch
• Condition: Neu
• Dimensions: 220W x 150H x 4D millimeters 220 millimeters width by 150 millimeters height by 4 millimeters depth
• Weight: 102 grams
• Seller catalogs:
  • Bücher

About this title

Synopsis

For the analysis of Rosuvastatin calcium, a specific and uncomplicated HPLC method was devised and validated. Rosuvastatin calcium belongs to the statin family, which is a reductase inhibitor for 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA). The medication is used to treat hypertension and ischemic coronary artery disease. It is also used to treat dyslipidemia and aid in the reduction of "bad cholesterol" levels. The technique was carried out on a C18 Column (250 4.6mm 1.d; 5) in isocratic mode with the mobile phase acetonitrile and water in the ratio 75:25 v/v. The wavelength is 242 nm, and the flow rate is 0.6 milliliters per minute.The linearity was discovered between 10 and 60µg/ml, with a correlation coefficient of 0.9998. The medication has a 3.643 retention time. Because the suggested method is simple, quick, accurate, precise, and repeatable, it can be used for routine quality control analysis of rosuvastatin in both pure and tablet dosage forms.