DNA-Encoded Chemical Libraries : Methods and Protocols

Language: English

Published by Springer, 2023

1071625470 / 9781071625477

Series: Book 157 of 382 - Methods in Molecular Biology

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Seller: AHA-BUCH GmbH, Einbeck, GermanyAHA-BUCH GmbH

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Druck auf Anfrage Neuware - Printed after ordering - This volume discusses protocols that cover synthesis, screening by selection, and analysis of DNA-encoded chemical libraries (DEL). Chapters in this book focus on methods used to practice DEL technology and include solution phase library synthesis using a variety of chemistries; DNA encoding of chemical structure; design, preparation and analysis of target proteins and tool compounds; screening of soluble protein targets by affinity selection; DEL qPCR, preparative PCR and DNA sequence analysis; computational methods used to analyze selections and choose compounds for resynthesis; and analysis of hit compounds. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Cutting-edge and comprehensive, DNA-Encoded Chemical Libraries:Methods and Protocols is a valuable resource for scientists interested in DEL technology for drug discovery, and will contribute to the continued advancement in this important field.

Seller Inventory # 9781071625477

Title
DNA-Encoded Chemical Libraries : Methods and Protocols
Author
David Israel
Publisher
Springer
Publication year
2023
Condition
Neu
Binding
Taschenbuch
Language
English
ISBN 10
1071625470
ISBN 13
9781071625477
Item weight
453 grams
Dimensions
254x178x13 mm
Series
Book 157 of 382: Methods in Molecular Biology

AHA-BUCH GmbH

Einbeck, Germany

5-star seller

AbeBooks seller since August 14, 2006

Shipping rates from Germany to U.S.A.

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