DNA-Encoded Library Technology for Drug Discovery

Liu, Guansai; Krusemark, Casey J; Li, Jin

ISBN 10: 1788014871 / ISBN 13: 9781788014878

Published by Royal Society of Chemistry, 2025

About this Item

Seller Inventory # 011754

Bibliographic Details

• Title: DNA-Encoded Library Technology for Drug Discovery
• Publisher: Royal Society of Chemistry
• Publication Date: 2025
• Language: English
• ISBN 10: 1788014871
• ISBN 13: 9781788014878
• Binding: Hardcover
• Condition: New

About this title

Synopsis

DNA-encoded libraries have numerous advantages over traditional screening methods, including easy identification of compounds and the large quantity of compounds that can be screened simultaneously.

This book provides a comprehensive guide to the implementation of DNA-encoded library technology (DELT) in drug discovery for screening and hit validation, illustrated with successful case studies.

A valuable resource for researchers in drug discovery, this book is complete with successful case studies to illustrate the best practice in implementation and operation of DELT.

About the Authors

Purdue University, USA

Dr Jin Li has over 30 years biopharmaceutical experience (at Protherics and AstraZeneca), with senior scientific and leadership roles in early stage research; as well as experience in initiating and leading major collaboration, research and outsourcing programmes. Before founding HitGen, he held Global Director positions of Compound Sciences and Computational Sciences at AstraZeneca. This included responsibility for computational chemistry, computational biology and compound collection enhancement. Dr Li completed his BSc at Sichuan University, and PhD in macromolecular sciences at Aston University. He then completed post-doctoral research in theoretical biochemistry at Manchester University, UK. Dr Li is also a Fellow of the Royal Society of Chemistry.