Title: DNA Methylation Microarrays: Experimental Design and Statistical Analysis (Chapman & Hall/CRC Biostatistics Series)
Publisher: CRC Press
Publication Date: 2008
Language: English
ISBN 10: 1420067273
ISBN 13: 9781420067279
Binding: Hardcover
Condition: Very Good
Dust Jacket Condition: No Jacket

About this title

Synopsis

Providing an interface between dry-bench bioinformaticians and wet-lab biologists, DNA Methylation Microarrays: Experimental Design and Statistical Analysis presents the statistical methods and tools to analyze high-throughput epigenomic data, in particular, DNA methylation microarray data. Since these microarrays share the same underlying principles as gene expression microarrays, many of the analyses in the text also apply to microarray-based gene expression and histone modification (ChIP-on-chip) studies.

After introducing basic statistics, the book describes wet-bench technologies that produce the data for analysis and explains how to preprocess the data to remove systematic artifacts resulting from measurement imperfections. It then explores differential methylation and genomic tiling arrays. Focusing on exploratory data analysis, the next several chapters show how cluster and network analyses can link the functions and roles of unannotated DNA elements with known ones. The book concludes by surveying the open source software (R and Bioconductor), public databases, and other online resources available for microarray research.

Requiring only limited knowledge of statistics and programming, this book helps readers gain a solid understanding of the methodological foundations of DNA microarray analysis.

About the Author

Sun-Chong Wang, Art Petronis

"About this title" may belong to another edition of this title.

Store Description

Mixed stock including modern fist editions.

Visit Seller's Storefront

Seller's business information

Bramble Books
United Kingdom

Sale & Shipping Terms

Terms of Sale

All descriptions are believed to be accurate. Please return any book for a refund if you are not satisfied.

Shipping Terms

Shipping costs are based on books weighing 2.2 LB, or 1 KG. If your book order is heavy or oversized, we may contact you to let you know extra shipping is required.

Shipping rates from United Kingdom to U.S.A.

Shipping rates from United Kingdom to U.S.A.
Order quantity	30 to 45 business days	10 to 15 business days
First item	US$ 15.97	US$ 18.63

Delivery times are set by sellers and vary by carrier and location. Orders passing through Customs may face delays and buyers are responsible for any associated duties or fees. Sellers may contact you regarding additional charges to cover any increased costs to ship your items.