Title: DNA Sensors and Inflammasomes (Volume 625) (Methods in Enzymology (Volume 625))
Publisher: Academic Press
Publication Date: 2019
Language: English
ISBN 10: 0128183594
ISBN 13: 9780128183595
Binding: Hardcover
Condition: New

About this title

Synopsis

DNA Sensors and Inflammasomes, Volume 625, the latest release in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. New sections in this release include Phosphorylation and dimerization of STING and IRF3, cGAS enzymology, Synthesis and identification of immuno-stimulatory CDNs, Tracking cGAS activity/ cGAMP formation using SPR/NMR, Using an enzyme coupled assay to track cGAS activity under steady states, Tracking the polymerization of DNA sensors, inflammasome receptors, and downstream signaling partners using FRET, NLRC4 structure, Tracking TREX1 activity, DNA association and dissociation kinetics of PARP1, and more.

Provides the authority and expertise of leading contributors from an international board of authors
Presents the latest release in the Methods in Enzymology series
Includes the latest information on DNA sensors and inflammasomes

About the Author

Jungsan Sohn is at Johns Hopkins School of Medicine, MD, USA

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