Deformable Microparticles with Multiple Functionsfor Drug Delivery : Development of a Multi-functional Red Blood Cell Analog Using Polyelectrolyte Complex Microparticles

Language: English

Published by VDM Verlag Dr. Müller, VDM Verlag Dr. Müller E.K., 2008

3639074955 / 9783639074956

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Seller: AHA-BUCH GmbH, Einbeck, GermanyAHA-BUCH GmbH

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nach der Bestellung gedruckt Neuware - Printed after ordering - Since the HIV epidemic of the 1990s, researchershave attempted to develop a red blood cell analog.Even though some of these substitutes are now inPhase III of clinical trials, their use is limitedby side effects and short half-life in the humanbody. As a result, there is still a need for aneffective erythrocyte analog with minimumimmunogenic and side effects, so that it can be usedfor multiple applications. Finding new approachesto develop more efficient blood substitutes will notonly bring valuable advances in the clinicalapproach, but also in the area of in vitro testingof medical devices.This work examined the feasibility of creating adeformable multi-functional, biodegradablebiocompatible particle for applications in drugdelivery and device testing. As a preliminaryevaluation, different types of microcapsules weresynthesized using natural and synthetic polymersvarious cross-linking agents, and diversemanufacturing techniques. After fullycharacterizing of each system, the most promisingred blood cell analog in terms of deformabilitystability and toxicity was determined.

Seller Inventory # 9783639074956

Title
Deformable Microparticles with Multiple Functionsfor Drug Delivery : Development of a Multi-functional Red Blood Cell Analog Using Polyelectrolyte Complex Microparticles
Author
Taili Thula
Publisher
VDM Verlag Dr. Müller, VDM Verlag Dr. Müller E.K.
Publication year
2008
Condition
Neu
Binding
Taschenbuch
Language
English
ISBN 10
3639074955
ISBN 13
9783639074956
Item weight
213 grams
Dimensions
220x150x8 mm

AHA-BUCH GmbH

Einbeck, Germany

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AbeBooks seller since August 14, 2006

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