Design and Analysis of Non-Inferiority Trials

Language: English

Published by Chapman And Hall/CRC Jun 2020, 2020

0367576910 / 9780367576912

Series: Book 65 of 155 - Chapman & Hall/CRC Biostatistics

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Seller: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, GermanyBuchWeltWeit Ludwig Meier e.K.

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This item is printed on demand - it takes 3-4 days longer - Neuware -The increased use of non-inferiority analysis has been accompanied by a proliferation of research on the design and analysis of non-inferiority studies. Using examples from real clinical trials, Design and Analysis of Non-Inferiority Trials brings together this body of research and confronts the issues involved in the design of a non-inferiority trial. Each chapter begins with a non-technical introduction, making the text easily understood by those without prior knowledge of this type of trial. Topics covered include:A variety of issues of non-inferiority trials, including multiple comparisons, missing data, analysis population, the use of safety margins, the internal consistency of non-inferiority inference, the use of surrogate endpoints, trial monitoring, and equivalence trialsSpecific issues and analysis methods when the data are binary, continuous, and time-to-eventThe history of non-inferiority trials and the design and conduct considerations for a non-inferiority trialThe strength of evidence of an efficacy finding and how to evaluate the effect size of an active control therapyA comprehensive discussion on the purpose and issues involved with non-inferiority trials, Design and Analysis of Non-inferiority Trials will assist current and future scientists and statisticians on the optimal design of non-inferiority trials and in assessing the quality of non-inferiority comparisons done in practice. 456 pp. Englisch.

Seller Inventory # 9780367576912

Title
Design and Analysis of Non-Inferiority Trials
Author
Ivan S. F. Chan
Publisher
Chapman And Hall/CRC Jun 2020
Publication year
2020
Condition
Neu
Binding
Taschenbuch
Language
English
ISBN 10
0367576910
ISBN 13
9780367576912
Item weight
687 grams
Dimensions
234x156x24 mm
Series
Book 65 of 155: Chapman & Hall/CRC Biostatistics

BuchWeltWeit Ludwig Meier e.K.

Bergisch Gladbach, Germany

5-star seller

AbeBooks seller since January 11, 2012

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BuchWeltWeit Ludwig Meier e.K.

Germany