Design and Development of Sildenafil citrate Mouth dissolving film: Mouth Dissolving Film

Patel, Dhaval, Patel, Mukesh, Patel, Kanu

ISBN 10: 3659408360 / ISBN 13: 9783659408366

Published by LAP LAMBERT Academic Publishing, 2013

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Bibliographic Details

• Title: Design and Development of Sildenafil citrate Mouth dissolving film: Mouth Dissolving Film
• Publisher: LAP LAMBERT Academic Publishing
• Publication Date: 2013
• Language: English
• ISBN 10: 3659408360
• ISBN 13: 9783659408366
• Binding: Paperback
• Condition: Like New
• Book Type: book

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Synopsis

Oral drug delivery is the most widely utilized route of administration among the entire route that has been explored for the systemic delivery of drug via various pharmaceutical products of different dosage form. The conventional tablet seems to be most popular because of its ease of transportation and low manufacturing cost as compare to others but poor patient compliance with whom experienced swallowing difficulties. In response to this mouth dissolving drug delivery system (MDDs) were developed as an alternative to tablet, capsule and syrup. A variety of MDDs like Mouth dissolving tablets (MDTs) and Mouth dissolving films (MDFs) were commercialized. This book describes the design and development of sildenafil citrate mouth dissolving film. As sildenafil citrate is a widely utilized drug for erectile dysfunction. This produced mouth dissolving film prepared by newer polymer Kollicoat protect and showed the good alternative for the other mouth dissolving film former, specially HPMC. Stevioside a natural sweetener used and showed the potency to mask the bitter taste of sildenafil citrate. Hence, MDF of sildenafil citrate provide good alternate to other available dosage form.

About the Author

Dhaval A. Patel, M.Pharm (Pharmaceutics), Studied at Shri B.M.Shah college of Pharmaceutical Education and Research, MODASA (G.T.U, AHMEDABAD), GUJARAT