Design & Evaluation of Controlled Release Matrix Tablets of Prazosin | Modern Management of Hypertension

Rajan Kothari (u. a.)

ISBN 10: 6138387821 / ISBN 13: 9786138387824

Published by LAP LAMBERT Academic Publishing, 2018

About this Item

Design & Evaluation of Controlled Release Matrix Tablets of Prazosin | Modern Management of Hypertension | Rajan Kothari (u. a.) | Taschenbuch | 76 S. | Englisch | 2018 | LAP LAMBERT Academic Publishing | EAN 9786138387824 | Verantwortliche Person für die EU: preigu GmbH & Co. KG, Lengericher Landstr. 19, 49078 Osnabrück, mail[at]preigu[dot]de | Anbieter: preigu.

Seller Inventory # 113655856

Bibliographic Details

• Title: Design & Evaluation of Controlled Release Matrix Tablets of Prazosin | Modern Management of Hypertension
• Publisher: LAP LAMBERT Academic Publishing
• Publication Date: 2018
• Language: English
• ISBN 10: 6138387821
• ISBN 13: 9786138387824
• Binding: Taschenbuch
• Condition: Neu
• Dimensions: 220W x 150H x 6D millimeters 220 millimeters width by 150 millimeters height by 6 millimeters depth
• Weight: 131 grams
• Seller catalogs:
  • Bücher

About this title

Synopsis

In the present study, we have prepared matrix tablet formulations using Prazocin as a model drug and Ethyl Cellulose, Two grades of Hydroxy Propyl Methyl Cellulose- HPMC-K4M & HPMC-K100M as polymers in different ratios. The developed matrix tablets were evaluated for different physical-chemical evaluations like drug content, hardness, friability, swelling index etc. All the formulations had shown the results within prescribed limits. The In vitro drug release study indicates that formulation PCF-7 containing EC, HPMC K100M in 1:2 ratio shown good release pattern for 14 hours compares to other formulations. The short-term stability study proved no change in the formulation of ageing and it indicates good stability.