Design of Organic Solids (Topics in Current Chemistry, 198)

Edwin Weber; Y. Aoyama, M.R. Caira; G.R. Desiraju; J.P. Glusker; A.D. Hamilton; R.E. Melendez; A. Nangia

ISBN 10: 3540646450 / ISBN 13: 9783540646457

Published by Springer, Germany, 1998

About this Item

3540646450. Hardcover, from closed pharmaceutical company library. English text. 230 pages, Author index for Volumes 151-198, illustrated with charts, tables and diagrams. Sections: Directional Aspects of Intermolecular Interactions; Supramolecular Synthons and Pattern Recognition; Hydrogen-Bonded Ribbons, Tapes and Sheets as Motifs for Crystal Engineering; Functional Organic Zeolite Analogues; Crystalline Polymorphism of Organic Compounds. Contents unread, as new, clean, tight and bright.

Seller Inventory # 030328

Bibliographic Details

• Title: Design of Organic Solids (Topics in Current Chemistry, 198)
• Publisher: Springer, Germany
• Publication Date: 1998
• Language: English
• ISBN 10: 3540646450
• ISBN 13: 9783540646457
• Binding: Hardcover
• Condition: Near Fine
• Dust Jacket Condition: No Jacket
• Book Type: Book
• Seller catalogs:
  • Chemistry

About this title

Synopsis

Considering the high level of our knowledge concerning covalent bond formation in the organic chemistry of molecules, our understanding of the principles involved in organic solid design is almost in its infancy. While chemists today are able to synthesize organic molecules of very high complexity using sophisticated methods of preparation, they lack general approaches enabling them to reliably predict organic crystalline or solid structures from molecular descriptors - no matter how simple they are. On the other hand, nearly all the organic matter surrounding us is not in the single-molecule state but aggregated and condensed to form liquid or solid molecular assemblages and structural arrays giving rise to the appearances and properties of organic compounds we usually observe. Obviously, the electrical, optical or magnetic properties of solid organic materials that are important requirements for future technologies and high-tech applications, as well as the stability and solubility behavior of a medicament depend on the structure of the molecule and the intramolecular forces, but even more decisively on the intermolecular forces, i. e. the packing structure of the molecules to which a general approach is lacking. This situation concerned ]. Maddox some years ago to such a degree that he described it as "one of the continuing scandals in the physical sciences" [see (1998) Nature 335:201; see also Ball, P. (1996) Nature 381:648]. The problem of predicting organic solid and crystal structures is very dif- cult.