Determination of Steroid Hormones and Related Compounds in Filtered and Unfiltered Water by Solid-Phase Extraction, Derivatization, and Gas Chromatography with Tandem Mass Spectrometry

Foreman, William T; Gray, James L; Barber, Larry B

ISBN 10: 1500223379 / ISBN 13: 9781500223373

Published by CreateSpace Independent Publishing Platform, 2014

About this Item

Print on Demand.

Seller Inventory # I-9781500223373

Bibliographic Details

• Title: Determination of Steroid Hormones and Related Compounds in Filtered and Unfiltered Water by Solid-Phase Extraction, Derivatization, and Gas Chromatography with Tandem Mass Spectrometry
• Publisher: CreateSpace Independent Publishing Platform
• Publication Date: 2014
• Language: English
• ISBN 10: 1500223379
• ISBN 13: 9781500223373
• Binding: Soft cover
• Condition: New

About this title

Synopsis

A new analytical method has been developed and implemented at the U.S. Geological Survey National Water Quality Laboratory that determines a suite of 20 steroid hormones and related compounds in filtered water (using laboratory schedule 2434) and in unfiltered water (using laboratory schedule 4434). This report documents the procedures and initial performance data for the method and provides guidance on application of the method and considerations of data quality in relation to data interpretation. The analytical method determines 6 natural and 3 synthetic estrogen compounds, 6 natural androgens, 1 natural and 1 synthetic progestin compound, and 2 sterols: cholesterol and 3-beta-coprostanol. These two sterols have limited biological activity but typically are abundant in wastewater effluents and serve as useful tracers. Bisphenol A, an industrial chemical used primarily to produce polycarbonate plastic and epoxy resins and that has been shown to have estrogenic activity, also is determined by the method.