Development & Characterization Of Ofloxacin & Prednisolone Loaded NLCs : A Nano-structured Lipid Carriers (NLCs)

Language: English

Published by LAP LAMBERT Academic Publishing, 2019

6139453348 / 9786139453344

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Seller: AHA-BUCH GmbH, Einbeck, GermanyAHA-BUCH GmbH

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nach der Bestellung gedruckt Neuware - Printed after ordering - The present study was designed to develop and characterize nanostructured lipid carriers (NLC) of Ofloxacin and Prednisolone for topical use in case of infections associated with inflammation. Ofloxacin was obtained as gift sample from Mankind Pharma Ltd, Vill Kyarta, P.O. Misserwal, Poonta Sahib, Sir Mour. H.P. Whereas Prednisolone was purchased from Yarrow chem., Mumbai. It was evaluated for its pre-formulation studies (organoleptic properties, melting point, solubility, compatibility, max. wavelength of absorption). In pre-formulation study, drugs were found having the similar properties as described in Indian Pharmacopoeia (IP) and United States Pharmacopoeia (USP). SEM photomicrograph revealed that NLCs were spherical with more or less smooth surface; particle size 512.3-1703 nm and PDI- 0.399-0.742 (ofloxacin) and particle size 539.3-1736.7 nm and PDI- 0.335 - 0.711 (prednisolone) etc. In conclusion, the prepared NLCs had prolonged release effects with good potential for topical delivery of NLC based gel formulation of ofloxacin & prednisolone.…

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Title
Development & Characterization Of Ofloxacin & Prednisolone Loaded NLCs : A Nano-structured Lipid Carriers (NLCs)
Author
Deeksha Sahai
Publisher
LAP LAMBERT Academic Publishing
Publication year
2019
Condition
Neu
Binding
Taschenbuch
Language
English
ISBN 10
6139453348
ISBN 13
9786139453344
Item weight
191 grams
Dimensions
220x150x8 mm

AHA-BUCH GmbH

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