Development and Validation of Analytical Method for lower dosage form | Different Spectrophotometric and Chromatographic methods for Quantification of Rasagiline

Publisher

LAP LAMBERT Academic Publishing

Publication Date

2011

Language

English

ISBN 10

3844384286

ISBN 13

9783844384284

Binding

Taschenbuch

Condition

Neu

Dimensions

Weight

298 grams

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Synopsis

To meet the emerging challenges of 21st century, the number of drugs introduced into the global pharmaceutical market is increasing every year. The focus on research and development of the drug molecule is to introduce either new entities or partial structural modification of the existing one to improve its potency and/or to reduce its adverse effect. Very often there is a time lag from the date of introduction of a drug into the market to the date of its inclusion in pharmacopoeias. This happens because of the possible uncertainties in the continuous and wider usage of these drugs, reports of new toxicities (resulting in their withdrawal from the market), development of patient resistance and introduction of better drugs by the competitors. Under these conditions, standard analytical procedures for these drugs may not be available in the pharmacopoeias. The analysis of high-potency, low-strength solid oral dosage forms poses a number of analytical challenges that can impact potency, purity and dissolution testing of the dosage form.

About the Author

Bhavinkumar K. Vaishnani, M.Pharmacy (Quality Assurance)from Rajiv Gandhi University of Health Science, Bangalore, INDIA

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