Development and validation of HPLC method for simultaneous quantitative determination of Azilsartan medoxomil potassium and Chlorthalidone in human plasma

Language: English

Published by GRIN Verlag, 2015

3656863148 / 9783656863144

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Druck auf Anfrage Neuware - Printed after ordering - Doctoral Thesis / Dissertation from the year 2014 in the subject Chemistry - Analytical Chemistry, grade: 3, Saurashtra University (Department of Chemistry), course: Ph.D., language: English, abstract: The objective of this work was to develop a simple, cost effective, rugged and a high throughput method for simultaneous estimation of Azilsartan and Chlorthalidone in human plasma. Solid phase extraction technique is introduced here for first time and its advantages are: (I) Short processing time, (II) Significant reduction in the labour and (III) This technique minimizes chances of errors, saves considerable time and simplifies the sample preparation methodology. The run time per sample analysis of 15.0 min suggests the high throughput of the proposed method. From the results of all the validation parameters, the method proposed here can be useful for therapeutic drug monitoring both for analysis of routine samples of single dose or multiple dose pharmacokinetics and also for the clinical trial samples.

Seller Inventory # 9783656863144

Title
Development and validation of HPLC method for simultaneous quantitative determination of Azilsartan medoxomil potassium and Chlorthalidone in human plasma
Author
Vijay Ram
Publisher
GRIN Verlag
Publication year
2015
Condition
Neu
Binding
Taschenbuch
Language
English
ISBN 10
3656863148
ISBN 13
9783656863144
Item weight
129 grams
Dimensions
210x148x6 mm

AHA-BUCH GmbH

Einbeck, Germany

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Shipping rates from Germany to U.S.A.

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