Dialysing for Life : The Development of the Artificial Kidney
Language: English
Published by Springer, 2001
- Softcover
- New

Seller: AHA-BUCH GmbH, Einbeck, GermanyAHA-BUCH GmbH
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Druck auf Anfrage Neuware - Printed after ordering - Seeing a patient die under his hands because there is no adequate treatment causes an emotion and a frustration in a doctor, which sometimes stimulates him to try to develop a new type of treatment. Seeing so many wounded young soldiers die due to renal failure in World War I incited the German doctor Georg Haas to try to develop an artificial kidney. He had to give up in despair in 1928. Ten years later doctor Willem Kolff saw a young man die in his ward in the University Hospital of Groningen due to renal failure. By that time two essential factors for an artificial kidney had become available: a drug to keep the blood from clotting outside of the body and an efficient dialysing membrane through which waste substances can pass from the blood into the dialysing fluid. Kolff succeeded in creating the rotating artificial kidney which he started using in the town hospital of Kampen in 1943. The rotation of this artificial kidney started a revolution that made it possible for thousands of kidney patients all over the world to keep on living - and sometimes to forget their disease for the time being. In addition it gave rise to the development of other artificial organs such as the heart-lung machine, the artificial heart and the artificial eye. Doctor Jacob van Noordwijk, the author of this book, was Kolff's first assistant in the treatment of the first 15 patients. How Kolff succeeded in spite of all the limitations imposed by the German occupation of the Netherlands and in spite of the absence of antibiotics and other medical tools which are common nowadays makes a story which may sound incredible. Yet it did happen and visitors to the town of Kampen can still see the hospital building where it all took place.…
Seller Inventory # 9780792368403
- Title
- Dialysing for Life : The Development of the Artificial Kidney
- Author
- J. van Noordwijk
- Publisher
- Springer
- Publication year
- 2001
- Condition
- Neu
- Binding
- Taschenbuch
- Language
- English
- ISBN 10
- 0792368401
- ISBN 13
- 9780792368403
- Item weight
- 213 grams
- Dimensions
- 235x155x8 mm
Ten years later doctor Willem Kolff saw a young man die in his ward in the University Hospital of Groningen due to renal failure. By that time two essential factors for an artificial kidney had become available: a drug to keep the blood from clotting outside of the body and an efficient dialysing membrane through which waste substances can pass from the blood into the dialysing fluid. Kolff succeeded in creating the rotating artificial kidney which he started using in the town hospital of Kampen in 1943. The rotation of this artificial kidney started a revolution that made it possible for thousands of kidney patients all over the world to keep on living - and sometimes to forget their disease for the time being. In addition it gave rise to the development of other artificial organs such as the heart-lung machine, the artificial heart and the artificial eye.
Doctor Jacob van Noordwijk, the author of this book, was Kolff's first assistant in the treatment of the first 15 patients. How Kolff succeeded in spite of all the limitations imposed by the German occupation of the Netherlands and in spite of the absence of antibiotics and other medical tools which are common nowadays makes a story which may sound incredible. Yet it did happen and visitors to the town of Kampen can still see the hospital building where it all took place.
"Synopsis" may belong to another edition of this title.
From The New England Journal of Medicine
Like many other therapeutic advances, the advent of dialysis was slow, and bursts of progress were based on the work of pioneers from various disciplines. Thomas Graham (1805-1869), a physical chemist, is credited for coining the term ``dialysis'' in his 1854 description of the diffusion of crystalloids and the movement of water across semipermeable membranes. Some 60 years later, the term ``artificial kidney'' was coined by a pharmacologist, John Abel (1857-1938), and his associates, who used the principle of diffusion for the removal of substances from the blood of rabbits and dogs by perfusing it in colloidin tubes immersed in a dialysate bath. In 1924, George Haas (1886-1971), a surgeon, performed dialysis in humans but gave up his efforts because of technical difficulties and limited clinical success. About 20 years later, hemodialysis became a reality through the pioneering work of an internist, Willem J. Kolff (born in 1910). The introduction of a permanent vascular-access device by another internist, Belding Scribner (born in 1920), allowed for long-term dialysis in 1960. Countless others, who contributed various components, modifications, and refinements to the seminal work of these investigators, have been instrumental in the development of a successful technology that replaces a failed kidney.
The story of dialysis has been told in several articles and books published over the past two decades. Like much of medical history written by physicians or medical scientists, these accounts center on the role of individual investigators in determining the course of events. This approach to history has been faulted as antiquated by modern historians for its failure to consider the sociological, political, environmental, and circumstantial influences that ultimately shape history. Nevertheless, the fact remains that there have been pathfinders in the history of science in general and of medicine in particular who, through their singular perseverance and dedication, have made breakthroughs for which they should be recognized according to any historical criteria. In the history of dialysis, the work of Willem J. Kolff is one such example, particularly when one considers the difficult circumstances in the Nazi-occupied Netherlands, the scarcity of resources, and the small hospital in Kampen where the artificial kidney was developed and shown to preserve life.
In Dialysing for Life, Jacob van Noordwijk, one of Kolff's assistants in Kampen, recounts the difficult but critical times in the development of the artificial kidney. His personal account, which constitutes the first half of this small book, provides invaluable insight into the stages of development of the artificial kidney, the preceptors and collaborators who stimulated and supported Kolff's work, and Kolff's immediate post-war efforts to promulgate the use of the artificial kidney for the treatment of acute renal failure. The second half of the book, although informative, is less valuable. It is selective in its coverage, delves into ethical and financial considerations on the basis of decade-old figures, and only superficially touches on the contributions of some of the key investigators in the early days of long-term maintenance dialysis.
Parts of the story have appeared in articles written in English by the author. Its availability as a book, translated from the Dutch, provides an informative, brief, and easy-to-read work for anyone interested in the history of dialysis. Particularly valuable are its illustrations, but the clarity of the reproductions is less than optimal. Most chapters are well annotated but have only selective reference lists. The book is not indexed. Van Noordwijk's first-hand account and perception of events in the first part of Dialysing for Life should provide future historians of medicine with a primary source of information when the history of dialysis is recounted more objectively, within the general context of the times.
Garabed Eknoyan, M.D.
Copyright © 2001 Massachusetts Medical Society. All rights reserved. The New England Journal of Medicine is a registered trademark of the MMS.
"About the title" may belong to another edition of this title.
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