Differentiation of Chiral Compounds Using NMR Spectroscopy

Thomas J. Wenzel

ISBN 10: 1119323916 / ISBN 13: 9781119323914

Published by John Wiley and Sons Inc, US, 2018

About this Item

An updated guide to the most current information available for determining how to use NMR spectroscopy to differentiate chiral compounds  Differentiation of Chiral Compounds Using NMR Spectroscopy offers a thoroughly revised second edition to the essential volume that puts the focus on the chiral systems that are commercially available and have been widely vetted for use in NMR spectroscopy. The text covers a broad range of reagents that make it possible to determine the enantiomeric purity and assign the absolute configuration of many classes of compounds. Comprehensive in scope, the text describes the chiral NMR differentiating agents as derivatizing agents, solvating agents, metal-based reagents and liquid crystals and gels, and explains the range and types of compounds for which they can be used for analysis. New to this edition are the most recent findings in the field as well as the development of advanced NMR measurement techniques that allow for the simplification of complex spectra resulting in more readily identified enantiodifferentiation. This important resource: Includes the most recent coverage of a large range of compounds that can be analyzed using chiral NMR reagentsExplores the use of chiral NMR reagents and explains their relationship to the stereochemistry of the analyzed moleculesOffers the essential information needed to help decide which method is the best NMR method to apply to a class or moleculesContains experimental strategies for using the reagents that are likely to improve the quality of the results Differentiation of Chiral Compounds Using NMR Spectroscopy is a comprehensive guide designed for investigators planning to use NMR spectroscopy to determine enantiomeric purity or assign the absolute configuration of a compound.

Seller Inventory # LU-9781119323914

Bibliographic Details

• Title: Differentiation of Chiral Compounds Using NMR Spectroscopy
• Publisher: John Wiley and Sons Inc, US
• Publication Date: 2018
• Language: English
• ISBN 10: 1119323916
• ISBN 13: 9781119323914
• Binding: Hardback
• Edition: 2nd Edition
• Condition: New
• Weight: 1436 grams

About this title

Synopsis

An updated guide to the most current information available for determining how to use NMR spectroscopy to differentiate chiral compounds 

Differentiation of Chiral Compounds Using NMR Spectroscopy offers a thoroughly revised second edition to the essential volume that puts the focus on the chiral systems that are commercially available and have been widely vetted for use in NMR spectroscopy. The text covers a broad range of reagents that make it possible to determine the enantiomeric purity and assign the absolute configuration of many classes of compounds.

Comprehensive in scope, the text describes the chiral NMR differentiating agents as derivatizing agents, solvating agents, metal-based reagents and liquid crystals and gels, and explains the range and types of compounds for which they can be used for analysis. New to this edition are the most recent findings in the field as well as the development of advanced NMR measurement techniques that allow for the simplification of complex spectra resulting in more readily identified enantiodifferentiation. This important resource:

• Includes the most recent coverage of a large range of compounds that can be analyzed using chiral NMR reagents
• Explores the use of chiral NMR reagents and explains their relationship to the stereochemistry of the analyzed molecules
• Offers the essential information needed to help decide which method is the best NMR method to apply to a class or molecules
• Contains experimental strategies for using the reagents that are likely to improve the quality of the results

Differentiation of Chiral Compounds Using NMR Spectroscopy is a comprehensive guide designed for investigators planning to use NMR spectroscopy to determine enantiomeric purity or assign the absolute configuration of a compound.

About the Author

THOMAS J. WENZEL, PHD, is the Charles A. Dana Professor of Chemistry at Bates College in Lewiston, Maine. He has served terms as chair of the Science Division, Chemistry Department, Biochemistry Program and the interdisciplinary Environmental Studies Program.