Christopher M. Cheatum and Amnon Kohen, Relationship of Femtosecond–Picosecond Dynamics to Enzyme-Catalyzed H-Transfer. Cindy Schulenburg and Donald Hilvert, Protein Conformational Disorder and Enzyme Catalysis. A. Joshua Wand, Veronica R. Moorman and Kyle W. Harpole, A Surprising Role for Conformational Entropy in Protein Function. Travis P. Schrank, James O. Wrabl and Vincent J. Hilser, Conformational Heterogeneity Within the LID Domain Mediates Substrate Binding to Escherichia coli Adenylate Kinase: Function Follows Fluctuations. Buyong Ma and Ruth Nussinov, Structured Crowding and Its Effects on Enzyme Catalysis. Michael D. Daily, Haibo Yu, George N. Phillips Jr and Qiang Cui, Allosteric Activation Transitions in Enzymes and Biomolecular Motors: Insights from Atomistic and Coarse-Grained Simulations. Karunesh Arora and Charles L. Brooks III, Multiple Intermediates, Diverse Conformations, and Cooperative Conformational Changes Underlie the Catalytic Hydride Transfer Reaction of Dihydrofolate Reductase. Steven D. Schwartz, Protein Dynamics and the Enzymatic Reaction Coordinate.

From the Back Cover

Christopher M. Cheatum and Amnon Kohen
Relationship of Femtosecond–Picosecond Dynamics to Enzyme-Catalyzed H-Transfer

Cindy Schulenburg and Donald Hilvert
Protein Conformational Disorder and Enzyme Catalysis

A. Joshua Wand, Veronica R. Moorman and Kyle W. Harpole
A Surprising Role for Conformational Entropy in Protein Function

Travis P. Schrank, James O. Wrabl and Vincent J. Hilser
Conformational Heterogeneity Within the LID Domain Mediates Substrate Binding to Escherichia coli Adenylate Kinase: Function Follows Fluctuations

Buyong Ma and Ruth Nussinov
Structured Crowding and Its Effects on Enzyme Catalysis

Michael D. Daily, Haibo Yu, George N. Phillips Jr and Qiang Cui
Allosteric Activation Transitions in Enzymes and Biomolecular Motors: Insights from Atomistic and Coarse-Grained Simulations

Karunesh Arora and Charles L. Brooks III
Multiple Intermediates, Diverse Conformations, and Cooperative Conformational Changes Underlie the Catalytic Hydride Transfer Reaction of Dihydrofolate Reductase

Steven D. Schwartz
Protein Dynamics and the Enzymatic Reaction Coordinate

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