Effect of polymers on release pattern of Ondansetron HCl matrix tablet

Asim Mehmood

ISBN 10: 3330854839 / ISBN 13: 9783330854833

Published by Noor Publishing Mär 2017, 2017

About this Item

This item is printed on demand - Print on Demand Titel. Neuware -The book is about to determine the release pattern of Ondansetron from bioadhesive polymers. CMC, HPMC and Carbopol were used as polymers. Direct compressed tablets were assessed for physical and chemical testing. The formulations containing carbopol and HPMC presented improved bio-adhesion and in-vitro release. The order of bioadhesion with relative to polymers was as Carbopol 934P > HPMC > CMC. Formulations A-5, A-10 and A-12 were the optimum as they followed zero order and Higuchi kinetic model presenting sustained release mechanisms as there R2 values are 0.960, 0.985 and 0.984 respectively.Books on Demand GmbH, Überseering 33, 22297 Hamburg 96 pp. Englisch.

Seller Inventory # 9783330854833

Bibliographic Details

• Title: Effect of polymers on release pattern of Ondansetron HCl matrix tablet
• Publisher: Noor Publishing Mär 2017
• Publication Date: 2017
• Language: English
• ISBN 10: 3330854839
• ISBN 13: 9783330854833
• Binding: Taschenbuch
• Condition: Neu
• Dimensions: 220W x 150H x 7D millimeters 220 millimeters width by 150 millimeters height by 7 millimeters depth
• Weight: 161 grams

About this title

Synopsis

The book is about to determine the release pattern of Ondansetron from bioadhesive polymers. CMC, HPMC and Carbopol were used as polymers. Direct compressed tablets were assessed for physical and chemical testing. The formulations containing carbopol and HPMC presented improved bio-adhesion and in-vitro release. The order of bioadhesion with relative to polymers was as Carbopol 934P > HPMC > CMC. Formulations A-5, A-10 and A-12 were the optimum as they followed zero order and Higuchi kinetic model presenting sustained release mechanisms as there R2 values are 0.960, 0.985 and 0.984 respectively.

About the Author

Asim Mehmood (B.Pharmacy, M.Phil.Pharmaceutics, MS Health Informatics)Lecturer (Department of health information management and technology, Faculty of public health and tropical medicine, Jazan University, Saudi Arabia)