Title: The Elimination and Toxicity of Caffein in Nephrectomized Rabbits Classic Reprint
Publisher: Forgotten Books
Publication Date: 2018
Language: English
ISBN 10: 1332259286
ISBN 13: 9781332259281
Binding: PAP
Condition: New
Weight: 118 grams

About this title

Synopsis

Caffeine elimination involves the kidney, stomach, and intestines, and this study tests what happens when the kidneys are removed.

It shows how the body shifts to other routes without creating a new excretory mechanism.

This work examines how the body rids itself of caffeine when both kidneys are removed in rabbits. It compares normal elimination with what can occur through the digestive tract and bile, and it looks for signs of compensatory pathways. The findings clarify how the gastrointestinal tract contributes to processing caffeine and how this differs from true excretion.

The research builds on a long history of studying how organs other than the kidney handle substances that are normally cleared by renal function. It details experiments that track caffeine moves through the stomach, intestines, bile, and urine, and it discusses how diet influences elimination through the gut. The result is a clearer picture of the limits of vicarious elimination in physiology and toxicology.

How caffeine is eliminated by stomach and intestines, not solely by the kidney
What changes after double nephrectomy in the rabbit’s eliminative processes
Evidence that the GI tract stores caffeine temporarily and returns it to circulation rather than excreting it
Impact of surgical manipulation on caffeine toxicity and absorption in nephrectomized subjects

Ideal for readers of early 20th‑century physiology and pharmacology, as well as those curious about how the body handles foreign substances when a key organ is removed.

"About this title" may belong to another edition of this title.

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