Emerging Therapies Targeting the Pathophysiology of Sickle Cell Disease, an Issue of Hematology/Oncology Clinics (The Clinics: Internal Medicine)

Elliott Vichinsky

ISBN 10: 0323289991 / ISBN 13: 9780323289993

Published by Elsevier, 2014

About this Item

1st edition. 1 pages. 9.20x6.10x0.80 inches. In Stock.

Seller Inventory # __0323289991

Bibliographic Details

• Title: Emerging Therapies Targeting the Pathophysiology of Sickle Cell Disease, an Issue of Hematology/Oncology Clinics (The Clinics: Internal Medicine)
• Publisher: Elsevier
• Publication Date: 2014
• Language: English
• ISBN 10: 0323289991
• ISBN 13: 9780323289993
• Binding: Hardcover
• Condition: Brand New
• Weight: 0.59 kilograms

About this title

Synopsis

This issue of Hematology/Oncology Clinics, guest edited by Dr. Elliott Vichinsky, is devoted to Sickle Cell Disease, and focuses on pathophysiology of hemoglobinopathies, therapeutic targets, and new approaches to correcting ineffective erythropoiesis and iron dysregulation. Articles in this issue include Polymerization and red cell membrane changes; Overview on reperfusion injury in the pathophysiology of SCD; Regulation of ineffective erythropoiesis in iron metabolism; Altering oxygen affinity; Cellular adhesion and the endothelium; Arginine therapy; Role of the hemostatic system on SCD pathophysiology and potential therapeutics; Adenosine signaling and novel therapies; New approaches to correcting ineffective erythropoiesis and iron dysregulation; New approaches to correcting ineffective erythropoiesis and iron dysregulation; Fetal hemoglobin induction; Gene therapy for hemoglobinopathies; and Oxidative injury and the role of antioxidant therapy.