Endocrine Disruptors - A Major Medical Challenge | An Impact of Endocrine Disruptors on Endocrine System: their Estrogenic Mechanism in In vitro and In vivo Models

Publisher

LAP LAMBERT Academic Publishing

Publication Date

2010

Language

English

ISBN 10

3843370230

ISBN 13

9783843370233

Binding

Taschenbuch

Condition

Neu

Dimensions

Weight

191 grams

Seller catalogs

B�cher

About this title

Synopsis

Exposure to Endocrine Disruptors (EDs) with estrogen like activities during late pregnancy can induce temporal and specific alterations in gene expression profiles in the uteri of dams and neonates, most likely reflecting the temporal susceptibility of the reproductive tract to estrogenic EDs in which some estrogen responsive expressed markedly in the uterus of neonates. In addition, results from our experiments demonstrate the involvement of various signaling pathways in response to E2 and EDs in vitro and in vivo. These EDs may trigger the induction of CaBP-9k, a useful biomarker for screening the estrogenicity of EDs, via an estrogen receptor mediated pathways in animal and cellular models. Furthermore, non-genomic pathways appear to be involved in the induction of CaBP-9k expression by estrogen or estrogenic compounds. Taken together, these results indicated that both genomic and non- genomic actions are required to induce and modulate an ED- response in vitro and in vivo in which non- genomic responses occur rapidly, often within minutes of exposure, whereas genomic responses are delayed and require at least several hours to become established.

About the Author

Hoang Vu Dang earned his Master and continued his study for Ph.D. training program at Chungbuk National University in Korea. After graduate, he has been awarded U.S. NIH funded postdoctoral fellowship in University of Rhode Island. Currently, he is working as JSPS postdoctoral fellow in Research Team for Advanced Biologics of NIAH in JAPAN

"About this title" may belong to another edition of this title.

Store Description

preigu betreibt einen Onlineversandhandel mit �ber 1 Mio. Produkten in verschiedenen Sortimenten. Das Kernsortiment besteht aus B�chern, Medien und Spielwaren. Ein gelungenes Einkaufserlebnis ist das Ziel einer jeden Bestellung bei preigu, denn der Kunde und seine Zufriedenheit stehen an erster Stelle. preigu setzt daher auf einen kompetenten Kundenservice, funktionierende Prozesse und schnelle Reaktion.

Visit Seller's Storefront

Seller's business information

preigu GmbH & Co. KG
Lengericher Landstra�e 19, Osnabr�ck, 49078, Germany

Sale & Shipping Terms

Terms of Sale

Standard Business Terms and customer information

I. Standard business terms

� 1 Basic provisions

(1) The following terms and conditions of business apply for all contracts concluded with us as the supplier (preigu GmbH & Co. KG) via the websites AbeBooks and/or ZVAB. Unless otherwise agreed, the inclusion of your own terms and conditions is explicitly rejected.

(2) A ?consumer' in the sense of the following regulations is every natural person who concludes a legal transaction which, to an overwh...

More Information

Shipping Terms

Shipping rates from Germany to U.S.A.

Shipping rates from Germany to U.S.A.
Order quantity	60 to 60 business days	60 to 60 business days
First item	US$ 80.33	US$ 80.33

Delivery times are set by sellers and vary by carrier and location. Orders passing through Customs may face delays and buyers are responsible for any associated duties or fees. Sellers may contact you regarding additional charges to cover any increased costs to ship your items.