Enzyme Kinetics : From Diastase to Multi-Enzyme Systems

Arthur R. Schulz

ISBN 10: 0521449502 / ISBN 13: 9780521449502

Published by Cambridge University Press, 1994

About this Item

Druck auf Anfrage Neuware - Printed after ordering - This text covers the field of steady-state kinetics from basic principles to the control of the multi-enzyme systems which constitute metabolic pathways. Emphasis is placed on the interpretation of the kinetic behaviour of enzyme-catalyzed reactions in terms of mechanisms. Algorithms are developed which can be implemented in computer programs for the derivation of equations. The treatment of steady-state enzyme kinetics is extended to allosteric enzymes and subunit interactions in polymeric enzymes. Principles are presented which provide for mathematical analysis of the control of multi-enzyme systems. Problems are included at the end of each chapter and their solutions are found at the end of the book. This book will be a useful text for advanced undergraduates and graduate students taking courses in enzyme chemistry and enzyme kinetics.

Seller Inventory # 9780521449502

Bibliographic Details

• Title: Enzyme Kinetics : From Diastase to Multi-Enzyme Systems
• Publisher: Cambridge University Press
• Publication Date: 1994
• Language: English
• ISBN 10: 0521449502
• ISBN 13: 9780521449502
• Binding: Taschenbuch
• Condition: Neu
• Dimensions: 229W x 152H x 15D millimeters 229 millimeters width by 152 millimeters height by 15 millimeters depth
• Weight: 427 grams

About this title

Synopsis

This textbook for advanced courses in enzyme chemistry and enzyme kinetics covers the field of steady-state enzyme kinetics from the basic principles inherent in the Henri equation to the expressions that describe the control of multi-enzyme pathways. Steady-state kinetic equations are derived with the use of the connection matrix method, and an algorithm is developed that can be implemented easily for computer-based derivation of the equations. Throughout the book emphasis is placed on a proper interpretation of the kinetic behavior of multi-reactant enzymic reactions and on the interpretation of control coefficients in terms of metabolic control. Problems are included at the end of each chapter and their solutions are found at the end of the book.

From the Back Cover

This textbook for advanced courses in enzyme chemistry and enzyme kinetics covers the field of steady state enzyme kinetics from the basic principles inherent in the Henri equation to the expressions which describe the control of multi-enzyme pathways. Steady state kinetic equations are derived with the use of the connection matrix method, and an algorithm which can be implemented easily for computer-based derivation of the equations is developed. Throughout the book emphasis is placed on a proper interpretation of the kinetic behavior of multi-reactant enzymic reactions. The principles of analytical geometry and basic calculus are employed to analyze non-hyperbolic substrate saturation curves in terms of the mechanisms, including subunit interactions, which cause the deviation from hyperbolic curves. Sensitivity theory is employed to obtain expressions for flux and concentration control coefficients for multi-enzyme pathways. The algorithm developed can be incorporated into a computer-based program for derivation. Emphasis is placed on the interpretation of control coefficients in terms of metabolic control. Problems are included at the end of each chapter and their solutions are found at the end of the book.