Epigenetic Gene Expression and Regulation

Suming Huang

ISBN 10: 0127999582 / ISBN 13: 9780127999586

Published by Elsevier Science Dez 2015, 2015

About this Item

This item is printed on demand - it takes 3-4 days longer - Neuware - Epigenetic Gene Expression and Regulation reviews current knowledge on the heritable molecular mechanisms that regulate gene expression, contribute to disease susceptibility, and point to potential treatment in future therapies. The book shows how these heritable mechanisms allow individual cells to establish stable and unique patterns of gene expression that can be passed through cell divisions without DNA mutations, thereby establishing how different heritable patterns of gene regulation control cell differentiation and organogenesis, resulting in a distinct human organism with a variety of differing cellular functions and tissues. The work begins with basic biology, encompasses methods, cellular and tissue organization, topical issues in epigenetic evolution and environmental epigenesis, and lastly clinical disease discovery and treatment. Each highly illustrated chapter is organized to briefly summarize current research, provide appropriate pedagogical guidance, pertinent methods, relevant model organisms, and clinical examples. 482 pp. Englisch.

Seller Inventory # 9780127999586

Bibliographic Details

• Title: Epigenetic Gene Expression and Regulation
• Publisher: Elsevier Science Dez 2015
• Publication Date: 2015
• Language: English
• ISBN 10: 0127999582
• ISBN 13: 9780127999586
• Binding: Buch
• Condition: Neu

About this title

Synopsis

Epigenetic Gene Expression and Regulation reviews current knowledge on the heritable molecular mechanisms that regulate gene expression, contribute to disease susceptibility, and point to potential treatment in future therapies.

The book shows how these heritable mechanisms allow individual cells to establish stable and unique patterns of gene expression that can be passed through cell divisions without DNA mutations, thereby establishing how different heritable patterns of gene regulation control cell differentiation and organogenesis, resulting in a distinct human organism with a variety of differing cellular functions and tissues.

The work begins with basic biology, encompasses methods, cellular and tissue organization, topical issues in epigenetic evolution and environmental epigenesis, and lastly clinical disease discovery and treatment.

Each highly illustrated chapter is organized to briefly summarize current research, provide appropriate pedagogical guidance, pertinent methods, relevant model organisms, and clinical examples.

• Reviews current knowledge on the heritable molecular mechanisms that regulate gene expression, contribute to disease susceptibility, and point to potential treatment in future therapies
• Helps readers understand how epigenetic marks are targeted, and to what extent transgenerational epigenetic changes are instilled and possibly passed onto offspring
• Chapters are replete with clinical examples to empower the basic biology with translational significance
• Offers more than 100 illustrations to distill key concepts and decipher complex science

From the Back Cover

Epigenetic Gene Expression and Regulation reviews current knowledge on the heritable molecular mechanisms that regulate gene expression, contribute to disease susceptibility, and point to potential treatment in future therapies.
The book shows how these heritable mechanisms allow individual cells to establish stable and unique patterns of gene expression which can be passed through cell divisions without DNA mutations. It therefore establishes how different heritable patterns of gene regulation control cell differentiation and organogenesis result in a distinct human organism with a variety of differing cellular functions and tissues.
The work begins with basic biology, encompasses methods, cellular and tissue organization, topical issues in epigenetic evolution and environmental epigenesis, and lastly clinical disease discovery and treatment. Each highly-illustrated chapter is organized to briefly summarize current research, provide appropriate pedagogical guidance, pertinent methods, relevant model organisms, and clinical examples.