Epigenetic Targets in Drug Discovery (Methods & Principles in Medicinal Chemistry) (Volume 42)

Sippl, W (ed)

ISBN 10: 3527323554 / ISBN 13: 9783527323555

Published by Wiley-VCH, 2009

About this Item

Volume 42. This is an ex-library book and may have the usual library/used-book markings inside.This book has hardback covers. In poor condition, suitable as a reading copy. No dust jacket. Please note the Image in this listing is a stock photo and may not match the covers of the actual item,800grams, ISBN:9783527323555.

Seller Inventory # 9794490

Bibliographic Details

• Title: Epigenetic Targets in Drug Discovery (Methods & Principles in Medicinal Chemistry) (Volume 42)
• Publisher: Wiley-VCH
• Publication Date: 2009
• Language: English
• ISBN 10: 3527323554
• ISBN 13: 9783527323555
• Binding: Hardcover
• Condition: Poor
• Weight: 800 grams
• Seller catalogs:
  • Medicine

About this title

Synopsis

Fueled by the expertise of a team of international specialist authors, this first reference on the booming topic covers everything a drug researcher needs to know about targeting epigenetic mechanisms of disease.
The first part of the book surveys current methodologies for finding and validating drug candidates that act via epigenetic mechanisms. The second part systematically surveys known and suspected drug targets within the epigenetic machinery, including the discovery and development of vorinostat, the first marketed epigenetic drug.

About the Author

Wolfgang Sippl is the head of Pharmaceutical and Medicinal Chemistry at the Martin-Luther University of Halle-Wittenberg (Germany). He obtained his Ph.D. in Pharmaceutical Chemistry at University of Düsseldorf and was a post-doctoral fellow at the Université Louis-Pasteur in Strasbourg (France), where he worked with Camille G. Wermuth. He then took a senior researcher position in Düsseldorf before moving to the University of Halle-Wittenberg as a full professor in 2003. His main interests are focussed on medicinal chemistry, computational chemistry and drug design

Manfred Jung is Professor for Pharmaceutical and Medicinal Chemistry at the Albert-Ludwigs University of Freiburg (Germany). He obtained a Ph. D. in Pharmaceutical Chemistry from the University of Marburg, working subsequently as a postdoctoral fellow with T. Durst at the University of Ottawa (Canada). In 1994 he started his own group at the Institute of Pharmaceutical Chemistry at the University of Münster and in 2003 he moved to Freiburg to his current position. His main research focus is the synthesis of enzyme inhibitors and in-vitro assay development in the field of histone modifying enzymes.