Essentials of Pharmatoxicology in Drug Research, Volume 1: Toxicity and Toxicodynamics (Advances in Pharmaceutical Product Development and Research)

ISBN 10: 0443158401 / ISBN 13: 9780443158407

Published by Academic Press, 2023

About this Item

Seller Inventory # 401355833

Bibliographic Details

• Title: Essentials of Pharmatoxicology in Drug Research, Volume 1: Toxicity and Toxicodynamics (Advances in Pharmaceutical Product Development and Research)
• Publisher: Academic Press
• Publication Date: 2023
• Language: English
• ISBN 10: 0443158401
• ISBN 13: 9780443158407
• Binding: Soft cover
• Condition: New

About this title

Synopsis

Toxicity and Toxicodynamics, Volume One in the Essentials of Pharmatoxicology in Drug Research series provides an overview on the essentials of toxicology, risk assessment and the mechanisms. Topics discussed include the types of cellular responses to chemical toxicants, mechanisms of drug toxicity, and their relevance to pharmaceutical product development. The book examines omics and computer-aided technologies for mechanistic and predictive toxicology and covers state-of-art testing in the evaluation of detrimental pathways, dose selection in toxicity studies, as well as the role of regulatory agencies in toxicity studies.

In addition, there is also discussion on clinical interventions such as pharmacotherapy and managed care strategies for acute poisoning. This volume is a valuable resource to those learning more about the drug development process related to toxicology and those who want to get an update on newer concepts on the toxicology aspect of drug research.

• Examines toxicological risk assessment in drug research
• Discusses toxicity mechanisms
• Covers risk assessment and the use of omics and computational technologies in mechanistic and predictive toxicology
• Offers clinical interventions and managed care as a result of toxic injury and acute poisoning

About the Author

Dr Rakesh K Tekade, Assistant Professor of the Department of Pharmaceutics, investigates the design, development and characterization of targeted nanotechnology based formulations for the site specific delivery of therapeutic drugs, siRNA, microRNA, plasmids, proteins and peptide for the treatment of cancer. His current research encompasses development of novel polymeric nanomaterial for effective cytosolic delivery of anticancer bioactives. Dr Tekade’s research is focused on designing a new generation of nanoparticles, which could identify the cancer cells and selectively deliver anticancer drugs and genes to inhibit the growth of cancer while sparing healthy tissues. His research work involves the applications of polymer chemistry, nanotechnology, molecular biology, pharmacokinetics/pharmacodynamics and imaging techniques. Dr Tekade has over 70 publications, 01 patent, 7 book chapters, and 3 editorial articles. He has delivered several invited research talks and presented research finding in more than 30 scientific conferences.