Experimental Approaches to Detect EBV Adaptive Immunity

Epstein-Barr virus (EBV) has emerged as one of the most significant viral factors implicated in autoimmune and neurological diseases, particularly multiple sclerosis. This book provides a comprehensive overview of the cutting-edge immunological technologies used to investigate EBV-driven adaptive immune responses and their role in disease pathogenesis. Covering advanced methods such as immunofluorescence, MHC multimer technology, ELISpot, T-cell receptor sequencing, and PhIP-Seq, it combines theoretical foundations with detailed laboratory protocols and practical guidance. Drawing on the latest scientific evidence, the book demonstrates how these complementary approaches advance biomarker discovery, therapeutic development, and precision medicine. An essential resource for researchers, immunologists, virologists, neuroscientists, graduate students, and biomedical professionals working at the intersection of viral immunology and autoimmune disease.