Experimental Models in Serotonin Transporter Research

. Ed(s): Kalueff, Allan V.; LaPorte, Justin L.

ISBN 10: 0521514878 / ISBN 13: 9780521514873

Published by Cambridge University Press, 2010

About this Item

Introduces and explicates the role of the serotonin transporter (a key brain protein) in the human and animal brain. Editor(s): Kalueff, Allan V.; LaPorte, Justin L. Num Pages: 380 pages, 13 b/w illus. 8 colour illus. BIC Classification: PSAN. Category: (P) Professional & Vocational. Dimension: 228 x 152 x 22. Weight in Grams: 740. . 2010. Illustrated. hardcover. . . . .

Seller Inventory # V9780521514873

Bibliographic Details

• Title: Experimental Models in Serotonin Transporter Research
• Publisher: Cambridge University Press
• Publication Date: 2010
• Language: English
• ISBN 10: 0521514878
• ISBN 13: 9780521514873
• Binding: Hardcover
• Condition: New

About this title

Synopsis

The serotonin transporter is a key brain protein that modulates the reuptake of the neurotransmitter serotonin from synaptic spaces back into the presynaptic neuron. This control over neuronal signalling makes it a prime area of neuroscientific study. In this book an international team of top experts introduce and explicate the role of serotonin and the serotonin transporter in both human and animal brains. They demonstrate the relevance of the transporter and indeed the serotonergic system to substrates of neuropsychiatric disorders, and explain how this knowledge is translated into valid animal models that will help foster new discoveries in human neurobiology. Writing for graduate students and academic researchers, they provide a comprehensive coverage of a wide spectrum of data from animal experimentation to clinical psychiatry, creating the only book exclusively dedicated to this exciting new avenue of brain research.

About the Authors

Allan V. Kalueff is Assistant Professor of Physiology in the Department of Physiology and Biophysics at the Georgetown University Medical Center, Washington DC, USA. His research has been recognized by numerous prestigious scientific awards, and has focused on the role of the serotonin transporter as a contributor to neuropsychiatric disorders in various animal models.

Justin L. LaPorte is a member of the Society for Neuroscience. His research at the National Institute of Mental Health (Bethesda, USA) employs behavioral pharmacology and molecular genetics approaches to elucidate the pathogenetic mechanisms of psychiatric disorders such as depression, anxiety, and obsessive-compulsive disorder, with a specific focus on the role of serotonin transporter.