Extracellular Matrix in Development

DeSimone, Douglas W.|Mecham, Robert P.

ISBN 10: 3642359345 / ISBN 13: 9783642359347

Published by Springer Berlin Heidelberg, 2013

About this Item

Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Gives a comprehensive and up to date overview on the fieldWritten by experts in the fieldCovers the role of ECM in development from all anglesPart I Informational signals in extracellular matrix and matrix influences on cell move.

Seller Inventory # 5058128

Bibliographic Details

• Title: Extracellular Matrix in Development
• Publisher: Springer Berlin Heidelberg
• Publication Date: 2013
• Language: English
• ISBN 10: 3642359345
• ISBN 13: 9783642359347
• Binding: Gebunden
• Condition: New
• Seller catalogs:
  • Mathematik/Naturwissenschaften/Technik/Medizin

About this title

Synopsis

Cells in the developing embryo depend on signals from the extracellular environment to help guide their differentiation. An important mediator in this process is the extracellular matrix – secreted macromolecules that interact to form large protein networks outside the cell. During development, the extracellular matrix serves to separate adjacent cell groups, participates in establishing morphogenic gradients, and, through its ability to interact directly will cell-surface receptors, provides developmental clocks and positional information. This volume discusses how the extracellular matrix influences fundamental developmental processes and how model systems can be used to elucidate ECM function. The topics addressed range from how ECM influences early development as well as repair processes in the adult that recapitulate developmental pathways.

From the Back Cover

Cells in the developing embryo depend on signals from the extracellular environment to help guide their differentiation. An important mediator in this process is the extracellular matrix – secreted macromolecules that interact to form large protein networks outside the cell. During development, the extracellular matrix serves to separate adjacent cell groups, participates in establishing morphogenic gradients, and, through its ability to interact directly will cell-surface receptors, provides developmental clocks and positional information. This volume discusses how the extracellular matrix influences fundamental developmental processes and how model systems can be used to elucidate ECM function. The topics addressed range from how ECM influences early development as well as repair processes in the adult that recapitulate developmental pathways.

The series Biology of Extracellular Matrix is published in collaboration with the American Society for Matrix Biology.