Extracellular Matrix in Disease and Tissue Engineering

Language: English

Published by Springer, Palgrave Macmillan Jun 2026, 2026

3032226171 / 9783032226174

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Seller: buchversandmimpf2000, Emtmannsberg, BAYE, Germanybuchversandmimpf2000

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This item is printed on demand - Print on Demand Titel. Neuware -This book emphasizes the importance of the extracellular matrix (ECM) in diseases and explains how this knowledge can be applied to tissue engineering. It provides a comprehensive analysis of the extracellular matrix (ECM) as a key regulator of cellular behavior, tissue architecture, and pathological processes. Integrating current advances in matrix biology, it elucidates how ECM composition, mechanical properties and biochemical signaling shape normal physiology and diverse disease states. The book examines the bidirectional crosstalk between cells and the ECM, detailing how matrixderived cues influence organelle dynamics, intracellular signaling pathways, and gene regulatory networks. Chapters analyze the contribution of ECM remodeling to cancer initiation, tumor dormancy, metastatic competence, inflammatory responses, and fibrotic progression. Special emphasis is placed on collagen and its posttranslational modifications, highlighting how molecular and supramolecular features underpin ECM stability, tissue mechanics, and disease susceptibility. At the same time, the book looks at how important ECM mimicking and ECM-derived materials are for tissue engineering and regenerative medicine. These scaffolds, designed to mimic natural signals in the microenvironment, create platforms for tissue repair, guiding stem cell differentiation and modelling disease mechanisms that are more relevant to the body. By combining molecular knowledge with new biomaterial strategies, the book highlights the potential of ECM-based approaches for new therapies. This work is targeted towards researchers, clinicians and advanced trainees in cell biology, biomedical engineering, oncology and regenerative medicine. It helps to understand how the structure and function of the extracellular matrix (ECM) intersects with disease mechanisms and therapeutic development. By emphasising mechanistic depth and interdisciplinary perspectives, the text provides readers with the conceptual and methodological foundations essential for advancing ECM-focused research and designing the next generation of biomedical interventions.Springer-Verlag KG, Sachsenplatz 4-6, 1201 Wien 436 pp. Englisch.…

Seller Inventory # 9783032226174

Title
Extracellular Matrix in Disease and Tissue Engineering
Author
Trayambak Basak
Publisher
Springer, Palgrave Macmillan Jun 2026
Publication year
2026
Condition
Neu
Binding
Buch
Language
English
ISBN 10
3032226171
ISBN 13
9783032226174
Item weight
894 grams
Dimensions
241x160x28 mm

buchversandmimpf2000

Emtmannsberg, BAYE, Germany

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AbeBooks seller since January 23, 2017

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