Fast Dissolving Tablet Of An Anti-inflammatory Drug: Formulation And Optimization Of Fast Dissolving Tablet Of An Anti-inflammatory Drug By Different Methods

The oral route of drug administration is the New drug delivery systems like fast dissolving or orodispersible tablets that dissolve or disperse quickly in a few seconds after placement in the mouth without water can alleviate the problem of swallowing tablets. Meloxicam is a non steroidal anti-inflammatory drug prescribed for osteoarthritis and rheumatoid arthritis the diseases most prevalent in the geriatric patients. The preparations of anti-inflammatory drugs are meant to produce therapeutic effect immediately after their administration as inflammation is mostly an acute condition needed to be cured symptomatically as first line of treatment. Unfortunately meloxicam is poorly soluble drug having higher time of onset of action. As it is a BCS class –II drug its effect is dissolution rate limited. By improving the dissolution of meloxicam its time of onset of action can be reduced. The administration of meloxicam as fast dissolving formulation with improved dissolution may improve patient compliance by ease of taking medicine without need of water and with the will of actually taking medicine.

KALPEN N PATEL, M. PHARM in Pharmaceutical technology: Studied Shree Krishna Institute of Pharmacy, Shankhalpur, Becharaji, Mehsana at Gujarat Technological University. I completed my B. Pharm at Smt. B.N.B. Swaminarayan Pharmacy college, Salvav, Vapi