Fast Dissolving Tablets Of Chlorpromazine And Promethazine

Language: English

Published by LAP LAMBERT Academic Publishing Sep 2012, 2012

3659232467 / 9783659232466

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This item is printed on demand - Print on Demand Titel. Neuware -Chlorpromazine HCl and Promethazine HCl are potent anti-emetic. The central antimuscarinic actions of antihistamines are probably responsible for their anti-emetic effects. Fast dissolving tablets of Chlorpromazine HCl and Promethazine HCl were prepared using five superdisintegrants viz; sodium starch glycolate, crospovidone, croscarmellose, L-HPC and pregelatinised starch. The tablets were evaluated for weight variation, hardness, friability, disintegration time (1 min), dissolution rate, content uniformity, and were found to be within standard limit. It was concluded that the fast dissolving tablets with proper hardness, rapidly disintegrating with enhanced dissolution can be made using selected superdisintegrants. Among the different formulations of Chlorpromazine HCl and Promethazine HCl was prepared and studied and the formulation F2 and S2 containing crospovidone, mannitol and microcrystalline cellulose combination was found to be the fast dissolving formulation. In the present study an attempt has been made to prepare fast dissolving tablets of Chlorpromazine HCl and Promethazine HCl, by using different superdisintegrants with enhanced disintegration and dissolution rateOmniScriptum SRL, Str. Armeneasca 28/1, office 1, 2012 Chisinau 116 pp. Englisch.…

Seller Inventory # 9783659232466

Title
Fast Dissolving Tablets Of Chlorpromazine And Promethazine
Author
D. Bhikshapathi
Publisher
LAP LAMBERT Academic Publishing Sep 2012
Publication year
2012
Condition
Neu
Binding
Taschenbuch
Language
English
ISBN 10
3659232467
ISBN 13
9783659232466
Item weight
191 grams
Dimensions
220x150x8 mm

buchversandmimpf2000

Emtmannsberg, BAYE, Germany

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