This volume explores several aspects of how antibodies mediate their activity in vivo, ranging from cancer immunotherapy to autoimmunity, infection, and vaccination. Divided into seven chapters, it provides in-depth insights into how antibodies and especially the antibody fragment crystallizable (Fc) domain modulate immune responses and antibody activity. The book begins by discussing evolutionary aspects of how the family of Fc receptors that are the key molecules for antibody activity evolved. In turn, it addresses the molecular and cellular pathways underlying IgG activity in cancer immunotherapy, and focuses on how IgG glycosylation regulates IgG and IgE activity in autoimmunity, allergy and infection. In closing, it presents strategies for developing novel antibody-based vaccination approaches. The book is intended for a very broad readership, including graduate students, postdocs and principal investigators with a basic grasp of immunology.

About the Author

Jeffrey V. Ravetch

Theresa and Eugene M. Lang Professor

Department Leonard Wagner Laboratory of Molecular Genetics and Immunology

Rockefeller University

1230 York Avenue, Box 98

New York, NY 10021, USA

ravetch@mail.rockefeller.edu

Falk Nimmerjahn

Professor for Immunology and Genetics

Chairman of the Institute of Genetics

Head of the Department of Biology

Department of Biology

University of Erlangen-Nuernberg

Erwin-Rommelstr. 3

91058 Erlangen, Germany

falk.nimmerjahn@fau.de

"About this title" may belong to another edition of this title.

Store Description

Kennys.ie is the largest exporter of books from Ireland currently exporting to approximately 100 countries around the world. Kennys Bookshop houses hundreds of thousands of books and specialises in collection development and library services, supplying booksellers and state and university libraries on a global scale including the U.S.A.,Japan and Europe. Kennys.ie is Ireland's Largest Online Bookshop.

Visit Seller's Storefront

Seller's business information

Kennys Bookshop and Art Galleries Ltd.
Liosban Industrial Estate, Tuam Road, Galway, Ireland

Sale & Shipping Terms

Terms of Sale

Terms of Sale - Credit Cards: Visa, Master Card, American Express, Diner.
Payment can also be made by bank draft in Euros, drawn on an Irish Bank.

We regret that PO Boxes are not acceptable to the U.S. as our courier will not deliver to them.

In case of returns or queries please contact us by email books@kennys.ie or by phone +353 91 709350

VAT Registration - IE2238521A

Conor Kenny

Shipping Terms

Free Shipping

Shipping rates from Ireland to U.S.A.

Shipping rates from Ireland to U.S.A.
Order quantity	12 to 22 business days	10 to 20 business days
First item	US$ 12.22	US$ 13.38

Delivery times are set by sellers and vary by carrier and location. Orders passing through Customs may face delays and buyers are responsible for any associated duties or fees. Sellers may contact you regarding additional charges to cover any increased costs to ship your items.