Fermentative Production of Erythromycin: Lab-Scale Production of Erythromycin

Erythromycin producing bacteria Saccharopolyspora erythraea strain MTCC No. 1103 was purchased from MTCC, Chandigarh. Sporulation of this bacteria was done on Oat meal Agar medium at a temperature of about 30˚C. Optimization of the fermentation conditions was performed with different parameter,like temperature, pH, time etc. Fermentative production of erythromycin gave best results with a temperature of 30˚C at a pH of 7.5 in 5 days. Further research works are going on process optimization with shake flask & bioreactors.

Prof.(Dr.) A.N.Pathak Director, AmityInstitute of Biotechnology and Dean Research, AmityUniversity Rajasthan ,Jaipur-303002,India.PDF Stuttgart University(Germany);Ph.D.-I.I.T.Delhi FIEFellow of Institution of Engineers,Calcutta ,India;M.Tech. Bombay University, India.Teaching andResearch experience 38 years;Publications 60.